Page 64 - 79_03
P. 64
Regulación
de
la
neurotransmisión
glicinérgica…
32.
Sorkina
T.;
Miranda
M.;
Dionne
K.R.;
Hoover
B.R.;
Zahniser
N.R.;
Sorkin
A.
RNA
interference
screen
reveals
an
essential
role
of
Nedd4--2
in
dopamine
transporter
ubiquitination
and
endocytosis.
J.
Neurosci.
26,
8195--205
(2006).
33.
González--González
I.M.;
García--Tardón
N.;
Giménez
C.;
Zafra
F.
PKC--dependent
endocytosis
of
the
GLT1
glutamate
transporter
depends
on
ubiquitylation
of
lysines
located
in
a
C--
terminal
cluster.
Glia.
56,
963--74
(2008).
34.
Fujimuro
M.;
Yokosawa
H.
Production
of
antipolyubiquitin
monoclonal
antibodies
and
their
use
for
characterization
and
isolation
of
polyubiquitinated
proteins.
Methods
Enzymol.
399,
75--86
(2005).
35.
Zeilhofer
H.U.
The
glycinergic
control
of
spinal
pain
processing.
Cell.
Mol.
Life.
Sci.
62,
2027--35
(2005).
36.
Yoshikawa
S.;
Oguchi
T.;
Funahashi
Y.;
de
Groat
W.C.;
Yoshimura
N.
Glycine
Transporter
Type
2
(GlyT2)
Inhibitor
Ameliorates
Bladder
Overactivity
and
Nociceptive
Behavior
in
Rats.
Eur.
Urol.
(2012)
DOI:
http://dx.doi.org/10.1016/j.eururo.2012.01.044
37.
Haranishi
Y.;
Hara
K.;
Terada
T.;
Nakamura
S.;
Sata
T.
The
antinociceptive
effect
of
intrathecal
administration
of
glycine
transporter--2
inhibitor
ALX1393
in
a
rat
acute
pain
model.
Anesth.
Analg.
110,
615--21
(2010).
38.
Chen
H.;
Polo
S.;
Di
Fiore
P.P.;
De
Camilli
P.V.
Rapid
Ca2+--dependent
decrease
of
protein
ubiquitination
at
synapses.
Proc.
Natl.
Acad.
Sci.
USA.
100,14908--13
(2003).
39.
Mukhopadhyay
D.;
Riezman
H.
Proteasome--independent
functions
of
ubiquitin
in
endocytosis
and
signaling.
Science
315,
201--5
(2007).
449