Page 20 - 88_01

in avian leukosis virus-induced lymphomas: evidence for stage-spe- ANALES
cific events. Mol Cell Biol 9, 2657-2664 (1989). RANF
112. J. Kluiver et al., BIC and miR-155 are highly expressed in Hodgkin,
primary mediastinal and diffuse large B cell lymphomas. J Pathol www.analesranf.com
207, 243-249 (2005).
113. P. S. Eis et al., Accumulation of miR-155 and BIC RNA in human B Si desea citar nuestro artículo:
cell lymphomas. Proc Natl Acad Sci U S A 102, 3627-3632 (2005). ONCOmicroARNs y sus futuras aplicaciones farmacológicas
114. S. Costinean et al., Pre-B cell proliferation and lymphoblastic leu-
kemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Pedro Medina Vico
Proc Natl Acad Sci U S A 103, 7024-7029 (2006). An Real Acad Farm [Internet].
115. T. H. Thai et al., Regulation of the germinal center response by mi- An. Real Acad. Farm.Vol. 88. nº 1 (2022) · pp 7-18
croRNA-155. Science 316, 604-608 (2007). DOI: http://dx.doi.org/10.53519/analesranf.2022.88.01.00
116. A. Rodriguez et al., Requirement of bic/microRNA-155 for normal
immune function. Science 316, 608-611 (2007).
117. E. Vigorito et al., microRNA-155 Regulates the Generation of Im-
munoglobulin Class-Switched Plasma Cells. Immunity 27, 847-859
(2007).
118. E. Gottwein et al., A viral microRNA functions as an orthologue of
cellular miR-155. Nature 450, 1096-1099 (2007).
119. C. G. Liu et al., An oligonucleotide microchip for genome-wide mi-
croRNA profiling in human and mouse tissues. Proc Natl Acad Sci U
S A 101, 9740-9744 (2004).
120. N. Rosenfeld et al., MicroRNAs accurately identify cancer tissue ori-
gin. Nat Biotechnol 26, 462-469 (2008).
121. M. E. Gleave, B. P. Monia, Antisense therapy for cancer. Nat Rev
Cancer 5, 468-479 (2005).
122. M. S. Kumar et al., Suppression of non-small cell lung tumor deve-
lopment by the let-7 microRNA family. Proc Natl Acad Sci U S A
105, 3903-3908 (2008).
123. A. Esquela-Kerscher et al., The let-7 microRNA reduces tumor growth
in mouse models of lung cancer. Cell Cycle 7, (2008).
124. F. Yu et al., let-7 regulates self renewal and tumorigenicity of breast
cancer cells. Cell 131, 1109-1123 (2007).
125. J. Krutzfeldt et al., Silencing of microRNAs in vivo with 'antagomirs'.
Nature 438, 685-689 (2005).
126. J. Elmen et al., LNA-mediated microRNA silencing in non-human
primates. Nature 452, 896-899 (2008).
127. R. E. Lanford et al., Therapeutic silencing of microRNA-122 in pri-
mates with chronic hepatitis C virus infection. Science 327, 198-
201 (2010).
128. D. Grimm et al., Fatality in mice due to oversaturation of cellular
microRNA/short hairpin RNA pathways. Nature 441, 537-541
(2006).

OncomicroRNAs and their future pharmacological applications

18 Pedro Pablo Medina Vico
An. Real Acad. Farm. Vol. 88. Nº 1 (2022) · pp.7-18