Page 37 - 84_02
P. 37

59. Hall JM, Lee MK, Newman B, Morrow JE, Anderson                                                  M.ª del Carmen Avendaño López
     LA, Huey B, King MC. Linkage of early-onset
     familial breast cancer to chromosome 17q21. Science          nasopharyngeal carcinoma. J Clin Oncol 2009; 27:
     1990; 250: 1684-9.                                           799-804.

60. Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, et     75. Andtbacka RH, Kaufman HL, Collichio F, Amatruda
     al. A strong candidate for the breast and ovarian            T, et al. Talimogene Laherparepvec Improves Durable
     cancer susceptibility gene BRCA1. Science 1994;              Response Rate in Patients With Advanced Melanoma.
     266: 66-71.                                                  J Clin Oncol 2015; 33: 2780-8.

61. Sekar A, Bialas AR, de Rivera H, Davis A, et al.         76. Sandmair AM, Loimas S, Puranen P, Immonen A, et
     Schizophrenia risk from complex variation of                 al. Thymidine kinase gene therapy for human
     complement component 4. Nature 2016; 530: 177-83.            malignant glioma, using replication-deficient
                                                                  retroviruses or adenoviruses. Hum Gene Ther 2000;
62. Handyside AH, Kontogianni EH, Hardy K, Winston                11: 2197-205.
     RM. Pregnancies from biopsied human
     preimplantation embryos sexed by Y-specific DNA         77. Jin Z, Maiti S, Huls H, Sing H, Olivares S, et al. The
     amplifications. Nature 1990; 344: 25-6.                      hyperactive Sleeping Beauty transposase SB100X
                                                                  improves the genetic modification of T cells to
63. Jaenich R, MintzB. Simian virus 40 DNA squences in            express a chimeric antigen receptor. Gene Ther 2011;
     DNA of healthy adult mice derived from                       18: 849-56.
     primplantation blastocytes inyected with viral DNA.
     Proc Natl Acad Sci USA 1974; 71: 1.250-4.               78. Madan RA, Arlen PM, Mohebtash M, Hodge JW, et al.
                                                                  Prostvac-VF: a vector-based vaccine targeting PSA in
64. Thomas KR, Capecchi RM. Site-directed mutagenesis             prostate cancer. Expert Opin Invest Drugs 2009; 18:
     by gene targeting in mouse embryo-derived stem cells.        1001-11.
     Cell 1987; 51: 503-12.
                                                             79. Khuri FR, Kurie JM. Antisense approaches enter the
65. a) Wivel NA, Anderson WF. Human gene therapy.                 clinic. Clin Cancer Res 2000; 6: 1607-13.
     Public policy and regulatory issues. Cold Spring
     Harbor Monograph Archive 1999; Chapter 24, nº 36:       80. Moreno PM, Pego AP. Therapeutic antisense
     671-89. b) Anderson WF. The best of times, the worst         oligonucleotides against cancer: hurdling to the clinic.
     of times. Science 2000; 288: 627.                            Front Chem 2014; 2: 87.

66. Booth C, Gaspar HB. Pegademase bovine (PEG-ADA)          81. Barrangou R, Fremaux C, Deveau H, Richards M, et
     for the treatment of infants and children with severe        al. CRISPR provides acquired resistance against
     combined immunodeficiency (SCID). Biologics:                 viruses in prokaryotes. Science 2007; 23; 315: 1709-
     Targets and Therapy 2009; 3: 349-58.                         12.

67. Lehrmas S. Virus treatment questioned after gene         82. a) Mojica FJ, Juez G, Rodríguez-Valera F.
     therapy death. Nature 1999; 401: 517-8.                      Transcription at different salinities of Haloferax
                                                                  mediterranei sequences adjacent to partially modified
68. Nathwani AC, Reiss UM, Tuddenham EG, Rosales C,               PstI sites. Mol Microbiol 1993; 9: 613-21. b) Mojica
     et al. Long term safety and efficacy of factor IX gene       FJ, Díez-Villaseñor C, García-Martínez J, Soria E.
     therapy in hemophilia B. New England Journal of              Intervening sequences of regularly spaced prokaryotic
     Medicine 2014; 371; 1.994-2.004.                             repeats derive from foreign genetic elements. J Mol
                                                                  Evol. 2005; 60:174-82.
69. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz
     MA, et al. Embryonic stem cell lines derived from       83. Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA,
     human blastocysts. Science 1998; 282: 1145-7.                Charpentier E. A programmable dual-RNA-guided
                                                                  DNA endonuclease in adaptive bacteral immunity.
70. Wertz DW. Embryo and stem cell research in the                Science 2012; 337: 816-21.
     United States. History and politics. Gene Therapy
     2002; 9: 674-8.                                         84. Gasiunas G, Barrangou R, Horvath Ph, Siksnys V.
                                                                  Cas9–crRNA ribonucleoprotein complex mediates
71. Tang WW, Dietmann S, Irie N, Leitch HG, et al. A              specific DNA cleavage for adaptive immunity in
     Unique Gene Regulatory Network Resets the Human              bacteria. PNAS 2012 ; 109: 15539-40.
     Germline Epigenome for Development. Cell
     2015;161: 1.453-67.                                     85. Sander JD, Joung JK. CRISPR-Cas systems for
                                                                  editing, regulating and targeting genomes. Nature
72. Avendaño C, Menéndez JC. “Gene therapy” en                    Biotechnology 2014; 32: 347-55.
     “Medicinal Chemistry of Anticancer Drugs”, 2015,
     Ed. Elsevier, pág. 582 y siguientes.                    86. Nakade S, Tsubota T, Sakane Y, Kume S, et al.
                                                                  Microhomology-mediated end-joining-dependent
73. Ferguson MS, Lemoine NR, Wang Y. Systemic                     integration of donor DNA in cells and animals using
     Delivery of Oncolytic Viruses: Hopes and Hurdles.            TALENs and CRISPR/Cas9. Nature Communications
     Adv Virol 2012; 2012: 1-14.                                  2014; 5: 5560.

74. Pan J-J, Zhang SW, Chen C-B, Xiao S-W, et al. Effect     87. McCarthy J. 10 ways CRISPR (gene-editing) can fight
     of recombinant adenovirus-p53 combined with                  poverty. Global Citizen, 27 Nov. 2015.
     radiotherapy on long-term prognosis of advanced
                                                                             @Real Academia Nacional de Farmacia. Spain
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