Page 102 - 79_02
P. 102

A.	
  Gómez	
  et	
  col.	
  

	
  

     37.	
   Pamplona,	
   R.;	
   Barja,	
   G.	
   An	
   evolutionary	
   comparative	
   scan	
   for	
   longevity-­-related	
   oxidative	
  
          stress	
  resistance	
  mechanisms	
  in	
  homeotherms.	
  Biogerontology	
  2011;	
  12,	
  409:35	
  

     38.	
   Pamplona,	
   R.;	
   Barja,	
   G.	
   Highly	
   resistant	
   macromolecular	
   components	
   and	
   low	
   rate	
   of	
  
          generation	
   of	
   endogenous	
   damage:	
   two	
   key	
   traits	
   of	
   longevity.	
   Ageing	
   Res	
   Rev	
   2007;	
   6,	
  
          189–210	
  

     39.	
   Caro	
   P.,	
   Gómez	
   J.,	
   Sanz	
   A.,	
   Portero-­-Otín	
   M.,	
   Pamplona	
   R.,	
   Barja	
   G.	
   Effect	
   of	
   graded	
  
          corticosterone	
   treatment	
   on	
   aging-­-related	
   markers	
   of	
   oxidative	
   stress	
   in	
   rat	
   liver	
  
          mitochondria.	
  Biogerontology	
  2007;	
  8,	
  1–11	
  

     40.	
   Pamplona,	
   R.;	
   Barja,	
   G.;	
   Portero-­-Otín,	
   M.	
   Membrane	
   fatty	
   acid	
   unsaturation,	
   protection	
  
          against	
   oxidative	
   stress,	
   and	
   maximum	
   life	
   span:	
   a	
   homeoviscous-­-longevity	
   adaptation.	
  
          Ann	
  New	
  York	
  Acad	
  Sci	
  2002;	
  959,	
  475-­-490	
  

     41.	
   Pamplona,	
   R.;	
   Portero-­-Otín,	
   M.;	
   Requena,	
   J.R.;	
   Thorpe,	
   S.R.;	
   Herrero,	
   A.;	
   Barja,	
   G.	
   A	
   low	
  
          degree	
   of	
   fatty	
   acid	
   unsaturation	
   leads	
   to	
   lower	
   lipid	
   peroxidation	
   and	
   lipoxidation-­-
          derived	
   protein	
   modification	
   in	
   heart	
   mitochondria	
   of	
   the	
   longevous	
   pigeon	
   than	
   in	
   the	
  
          short-­-lived	
  rat.	
  Mech	
  Ageing	
  Dev	
  1999;	
  106,	
  283-­-296.	
  

     42.	
   Buttemer,	
   W.A.;	
   Battam,	
   H.;	
   Hulbert,	
   A.J.	
   Fowl	
   play	
   and	
   the	
   price	
   of	
   petrel:	
   long-­-living	
  
          Procellariformes	
   have	
   peroxidation-­-resistant	
   membrane	
   composition	
   compared	
   with	
  
          short-­-living	
  Galliformes.	
  Biol	
  Lett	
  2008;	
  4,	
  351-­-354	
  

     43.	
   Mitchell,	
   T.W.;	
   Buffenstein,	
   R.;	
   Hulbert,	
   A.J.;	
   Membrane	
   phospholipid	
   composition	
   may	
  
          contribute	
   to	
   exceptional	
   longevity	
   of	
   the	
   naked	
   mole-­-rat	
   (Heterocephalus	
   glaber):	
   A	
  
          comparative	
  study	
  using	
  shotgun	
  lipidomics.	
  Exp	
  Gerontol	
  2007;	
  42,	
  1053-­-1062.	
  

     44.	
  Hulbert,	
  A.J.;	
  Beard,	
  L.A.;	
  Grigg,	
  G.C.	
  The	
  exceptional	
  longevity	
  of	
  an	
  egg-­-laying	
  mammal,	
  the	
  
          short-­-beaked	
   echidna	
   (Tachyglossus	
   aculeatus)	
   is	
   associated	
   with	
   peroxidation-­-resistant	
  
          membrane	
  composition.	
  Exp	
  Gerontol	
  2008;	
  43,	
  729-­-733	
  

     45.	
   Hulbert,	
   A.J.;	
   Faulks,	
   S.C.;	
   Harper,	
   J.M.;	
   Miller,	
   R.A.;	
   Buffenstein,	
   R.	
   Extended	
   longevity	
   of	
  
          wild-­-derived	
  mice	
  is	
  associated	
  with	
  peroxidation-­-resistant	
  membranes.	
  Mech	
  Ageing	
  Dev	
  
          2006;	
  127,	
  653-­-657	
  

     46.	
  Pamplona,	
  R.;	
  Prat,	
  J.;	
  Cadenas,	
  S.;	
  Rojas,	
  C.,Pérez-­-Campo,	
  R.;	
  L6pez-­-Torres,	
  M.;	
  Barja	
  G.	
  Low	
  
          fatty	
  acid	
  unsaturation	
  protects	
  against	
  lipid	
  peroxidation	
  in	
  liver	
  mitochondria	
  from	
  long-­-
          lived	
   species:	
   the	
   pigeon	
   and	
   human	
   case.	
   Mechanisms	
  of	
  Ageing	
  and	
  Development	
   1996;	
  
          53,	
  86	
  53-­-66	
  

     47.	
   Vance,	
   D.E.;	
   Vance,	
   J.	
   Biochemistry	
   of	
   Lipids,	
   Lipoproteins	
   and	
   Membranes;	
   Bernardi,	
   G.,	
  
          Ed.;	
  New	
  Comprehensive	
  Biochemistry;	
  ELSEVIER,	
  1996;	
  31,	
  p	
  91	
  

     48.	
   Kastle,	
   M.;	
   Grune,	
   T.	
   Protein	
   oxidative	
   modification	
   in	
   the	
   aging	
   organism	
   and	
   the	
   role	
   of	
  
          the	
  ubiquitin	
  proteasomal	
  system.	
  Curr	
  Pharm	
  Des	
  2011;	
  17,	
  4007–4022	
  

     49.	
   Dhabi,	
   J.M.;	
   Monte,	
   P.L.;	
   Wingo,	
   J.;	
   Rowley,	
   B.C.;	
   Cao,	
   S.X.;	
   Waldford,	
   R.L.;	
   Spindler,	
   S.R.	
  
          Caloric	
   restriction	
   alters	
   the	
   feeding	
   response	
   of	
   key	
   metabolic	
   enzyme	
   genes.	
   Mech	
  
          Ageing	
  Dev	
  2001;	
  122,	
  1033–1048	
  

     50.	
  Caro,	
  P.;	
  Gómez,	
  J.;	
  López-­-Torres,	
  M.;	
  Sánchez,	
  I.;	
  Naudí,	
  A.;	
  Jove,	
  M.;	
  Pamplona,	
  R.;	
  Barja,	
  G.	
  
          Forty	
   percent	
   and	
   eighty	
   percent	
   methionine	
   restriction	
   decrease	
   mitochondrial	
   ROS	
  
          generation	
  and	
  oxidative	
  stress	
  in	
  rat	
  liver.	
  Biogerontology	
  2008;	
  9,	
  183–196	
  

     51.	
   Sanchez-­-Roman,	
   I.;	
   Gómez,	
   A.;	
   Pérez,	
   I.;	
   Sanchez,	
   C.;	
   Suarez,	
   H.;	
   Naudí,	
   A.;	
   Jové,	
   M.;	
   Lopez-­-
          Torres,	
  M.;	
  Pamplona,	
  R.;	
  Barja	
  G.	
  Effects	
  of	
  aging	
  and	
  methionine	
  restriction	
  applied	
  at	
  old	
  
          age	
  on	
  ROS	
  generation	
  and	
  oxidative	
  damage	
  in	
  rat	
  liver	
  mitochondria,	
  Biogerontol.	
  2012;	
  
          13,	
  399-­-411.	
  

     52.	
   Spiteller,	
   G.	
   Is	
   lipid	
   peroxidation	
   of	
   polyunsaturated	
   fatty	
   acids	
   the	
   only	
   source	
   of	
   free	
  
          radicals	
  that	
  induce	
  aging	
  and	
  age-­-related	
  diseases?	
  Rejuv	
  Res	
  2010;	
  13,	
  91-­-103	
  

     53.	
   Salminena,	
   A.;	
   Kaarniranta,	
   K.	
   AMP-­-activated	
   protein	
   kinase	
   (AMPK)	
   controls	
   the	
   aging	
  
          process	
  via	
  an	
  integrated	
  signaling	
  network.	
  Ageing	
  Research	
  Reviews	
  2012¸11,	
  230–	
  241	
  

     54.	
  Le	
  Bourg,	
  E.	
  Hormesis,	
  aging	
  and	
  longevity.	
  Biochim.	
  Biophys.	
  Acta.	
  2009;	
  1790,	
  1030–1039.	
  

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