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Alicia Rodríguez Gascón, M.ª Ángeles Solinís Aspiazu, Ana del Pozo Rodríguez

34. del Pozo-Rodríguez A, Delgado D, Solinís MA, et al.              gamma-zein. Angew Chem Int Ed Engl 2004; 43:
     Solid lipid nanoparticles as potential tools for gene           1811-4.
     therapy: in vivo protein expression after intravenous
     administration. Int J Pharm 2010; 385: 157-62.             48. Masuda T, Akita H, Harashima H. Evaluation of
                                                                     nuclear transfer and transcription of plasmid DNA
35. Delgado D, del Pozo-Rodríguez A, Solinís MA,                     condensed with protamine by microinjection: the use
     Bartkowiak A, Rodríguez-Gascón A. New gene                      of a nuclear transfer score. FEBS Lett 2005; 579:
     delivery system based on oligochitosan and solid lipid          2143-8.
     nanoparticles: 'in vitro' and 'in vivo' evaluation. Eur J
     Pharm Sci. 2013 Nov 20;50(3-4):484-91.                     49. Delgado D, Gascón AR, del Pozo-Rodríguez A, et al.
                                                                     Dextran-protamine-solid lipid nanoparticles as a non-
36. Battaglia L, Serpe L, Foglietta F, et al. Application of         viral vector for gene therapy: in vitro characterization
     lipid nanoparticles to ocular drug delivery. Expert             and in vivo transfection after intravenous
     Opin Drug Deliv 2016; 24: 1-15.                                 administration to mice. Int J Pharm 2012; 425: 35-43.

37. Gottfried LF, Dean DA. Extracellular and Intracellular      50. Ruponen M, Rönkkö S, Honkakoski P, Pelkonen J,
     Barriers to Non-Viral Gene Transfer. In: Wei M,                 Tammi M, Urtti A. Extracellular glycosaminoglycans
     Good D, Eds. Novel Gene Therapy Approaches.                     modify cellular trafficking of lipoplexes and
     Croatia: InTech 2013; pp.75-88.                                 polyplexes. J Biol Chem 2001; 276: 33875-80.

38. del Pozo-Rodríguez A, Delgado D, Solinís MA,                51. de la Fuente M, Seijo B, Alonso MJ. Novel hyaluronic
     Gascón AR, Pedraz JL. Solid lipid nanoparticles for             acid-chitosan nanoparticles for ocular gene therapy.
     retinal gene therapy: transfection and intracellular            Invest Ophthalmol Vis Sci 2008; 49: 2016-24.
     trafficking in RPE cells. Int J Pharm 2008; 360: 177-
     83.                                                        52. Apaolaza PS, Delgado D, del Pozo-Rodríguez A,
                                                                     Gascón AR, Solinís MÁ. A novel gene therapy vector
39. Ruiz de Garibay AP, Solinís MA, Rodríguez-Gascón                 based on hyaluronic acid and solid lipid nanoparticles
     A, Ganjian H, Fuchs R. Role of endocytic uptake in              for ocular diseases. Int J Pharm 2014; 465: 413-26.
     transfection efficiency of solid lipid nanoparticles-
     based nonviral vectors. J Gene Med 2013; 15: 427-40.       53. Ito T, Iida-Tanaka N, Niidome T et al. Hyaluronic
                                                                     acid and its derivative as a multi-functional gene
40. Delgado D, del Pozo-Rodríguez A, Solinís MA,                     expression enhancer: protection from non-specific
     Gascón A.R. Understanding the mechanism of                      interactions, adhesion to targeted cells, and
     protamine in solid lipid nanoparticle-based                     transcriptional activation. J Control Release 2006;
     lipofection: the importance of the entry pathway. Eur J         112: 382-8.
     Pharm Biopharm 2011; 79: 495-502.
                                                                54. Rosenberg SA, Aebersold P, Cornetta K, et al. Gene
41. Biegeleisen K. The probable structure of the                     transfer into humans--immunotherapy of patients with
     protamina-DNA complex. J Theor Biol 2006; 241:                  advanced melanoma, using tumor-infiltrating
     533-40.                                                         lymphocytes modified by retroviral gene transduction.
                                                                     N Engl J Med 1990; 323: 570-8.
42. Vighi E, Montanari M, Ruozi B, Tosi G, Magli A, Leo
     E. Nuclear localization of cationic solid lipid            55. Molday RS, Kellner U, Weber BH. X-linked juvenile
     nanoparticles containing protamine as transfection              retinoschisis: clinical diagnosis, genetic analysis, and
     promoter. Eur J Pharm Biopharm 2010; 76: 384-93.                molecular mechanisms. Prog Retin Eye Res 2012; 31:
                                                                     195-212.
43. del Pozo-Rodríguez A, Delgado D, Solinís MA,
     Gascón AR, Pedraz JL. Solid lipid nanoparticles:           56. Molday LL, Hicks D, Sauer CG, Weber BH, Molday
     formulation factors affecting cell transfection                 RS. Expression of X-linked retinoschisis protein RS1
     capacity. Int J Pharm 2007; 339: 261-8.                         in photoreceptor and bipolar cells. Invest Ophthalmol
                                                                     Vis Sci 2001; 42:8 16-25.
44. del Pozo-Rodríguez A, Delgado D, Gascón AR, Solinís
     MÁ. Lipid nanoparticles as drug/gene delivery              57. Sauer CG, Gehrig A, Warneke-Wittstock R, et al.
     systems to the retina. J Ocul Pharmacol Ther 2013;              Positional cloning of the gene associated with X-
     29: 173-88. doi: 10.1089/jop.2012.0128.                         linked juvenile retinoschisis. Nat Genet 1997; 17:
                                                                     164-70.
45. El-Sayed A, Khalil IA, Kogure K, Futaki S, Harashima
     H. Octaarginine- and octalysine-modified                   58. Weber BH, Schrewe H, Molday LL, et al. Inactivation
     nanoparticles have different modes of endosomal                 of the murine X-linked juvenile retinoschisis gene,
     escape. J Biol Chem 2008; 283: 23450-61.                        Rs1h, suggests a role of retinoschisin in retinal cell
                                                                     layer organization and synaptic structure. Proc Natl
46. del Pozo-Rodríguez A, Pujals S, Delgado D, et al. A              Acad Sci U S A 2002; 99: 6222-7.
     proline-rich peptide improves cell transfection of solid
     lipid nanoparticle-based non-viral vectors. J Control      59. Solinís MA, del Pozo-Rodríguez A, Apaolaza PS,
     Release 2009; 133: 52-9.                                        Rodríguez-Gascón A. Treatment of ocular disorders
                                                                     by gene therapy. Eur J Pharm Biopharm 2015; 95:
47. Fernández-Carneado J, Kogan MJ, Castel S, Giralt E.              331-42.
     Potential peptide carriers: amphipathic proline-rich
     peptides derived from the N-terminal domain of             60. Delgado D, Rodríguez-Gascón A, Solinís MA,
                                                                     Aspiazu MA, del Pozo-Rodríguez A, Pedraz JL.

422 @Real Academia Nacional de Farmacia. Spain
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