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SREBP-­-1c,	
  ChREBP	
  y	
  LXR…	
  

	
  

     94. Chen,	
  G.,	
  Liang,	
  G.,	
  Ou,	
  J.	
  y	
  col.	
  2004.	
  Central	
  role	
  for	
  liver	
  X	
  receptor	
  in	
  insulin-­-mediated	
  
          activation	
   of	
   Srebp-­-1c	
   transcription	
   and	
   stimulation	
   of	
   fatty	
   acid	
   synthesis	
   in	
   liver.	
   Proc	
  
          Natl	
  Acad	
  Sci	
  U	
  S	
  A	
  101,	
  11245-­-11250.	
  

     95. Ye,	
   J.,	
   DeBose-­-Boyd,	
   R.A.,	
   2011.	
   Regulation	
   of	
   cholesterol	
   and	
   fatty	
   acid	
   synthesis.	
   Cold	
  
          Spring	
  Harb	
  Perspect	
  Biol	
  3.	
  pii:	
  a0047	
  

     96. Bobard,	
   A.,	
   Hainault,	
   I.,	
   Ferré,	
   P.	
   y	
   col.	
   2005.	
   Differential	
   regulation	
   of	
   sterol	
   regulatory	
  
          element-­-binding	
   protein	
   1c	
   transcriptional	
   activity	
   by	
   insulin	
   and	
   liver	
   X	
   receptor	
   during	
  
          liver	
  development.	
  J	
  Biol	
  Chem	
  280,	
  199-­-206.	
  

     97. Horton,	
   J.D.,	
   Bashmakov,	
   Y.,	
   Shimomura,	
   I.,	
   Shimano,	
   H.,	
   1998.	
   Regulation	
   of	
   sterol	
  
          regulatory	
  element	
  binding	
  proteins	
  in	
  livers	
  of	
  fasted	
  and	
  refed	
  mice.	
  Proc	
  Natl	
  Acad	
  Sci	
  U	
  
          S	
  A	
  95,	
  5987-­-599217.	
  

     98. Hasty,	
   A.H.,	
   Shimano,	
   H.,	
   Yahagi,	
   N.,	
   Amemiya-­-Kudo,	
   M.	
   y	
   col.	
   2000.	
   Sterol	
   regulatory	
  
          element-­-binding	
  protein-­-1	
  is	
  regulated	
  by	
  glucose	
  at	
  the	
  transcriptional	
  level.	
  J	
  Biol	
  Chem	
  
          275,	
  31069-­-31077.	
  

     99. Dentin,	
  R.,	
  Pégorier,	
  J.P.,	
  Benhamed,	
  F.	
  y	
  col.	
  2004.	
  Hepatic	
  glucokinase	
  is	
  required	
  for	
  the	
  
          synergistic	
  action	
  of	
  ChREBP	
  and	
  SREBP-­-1c	
  on	
  glycolytic	
  and	
  lipogenic	
  gene	
  expression.	
  J	
  
          Biol	
  Chem	
  279,	
  20314-­-20326.	
  

     100. Liang,	
   G.,	
   Yang,	
   J.,	
   Horton,	
   J.D.	
   y	
   col.	
   2002.	
   Diminished	
   hepatic	
   response	
   to	
  
          fasting/refeeding	
   and	
   liver	
   X	
   receptor	
   agonists	
   in	
   mice	
   with	
   selective	
   deficiency	
   of	
   sterol	
  
          regulatory	
  element-­-binding	
  protein-­-1c.	
  J	
  Biol	
  Chem	
  277,	
  9520-­-9528.	
  

     101. Nagai,	
   Y.,	
   Yonemitsu,	
   S.,	
   Erion,	
   D.M.	
   y	
   col.	
   2009.	
   The	
   role	
   of	
   peroxisome	
  
          proliferator-­-activated	
  receptor	
  gamma	
  coactivator-­-1	
  beta	
  in	
  the	
  pathogenesis	
  of	
  fructose-­-
          induced	
  insulin	
  resistance.	
  Cell	
  Metab	
  9,	
  252-­-264.	
  

     102. Lee,	
   J.N.,	
   Zhang,	
   X.,	
   Feramisco,	
   J.D.	
   y	
   col.	
   2008.	
   Unsaturated	
   fatty	
   acids	
   inhibit	
  
          proteasomal	
   degradation	
   of	
   Insig-­-1	
   at	
   a	
   postubiquitination	
   step.	
   J	
   Biol	
   Chem	
   283,	
   33772-­-
          33783.	
  

     103. Kammoun,	
  H.L.,	
  Chabanon,	
  H.,	
  Hainault,	
  I.	
  y	
  col.	
  2009.	
  GRP78	
  expression	
  inhibits	
  
          insulin	
  and	
  ER	
  stress-­-induced	
  SREBP-­-1c	
  activation	
  and	
  reduces	
  hepatic	
  steatosis	
  in	
  mice.	
  J	
  
          Clin	
  Invest	
  119,	
  1201-­-1215.	
  

     104. Inoue,	
  J.,	
  Ito,	
  Y.,	
  Shimada,	
  S.	
  y	
  col.	
  2011.	
  Glutamine	
  stimulates	
  the	
  gene	
  expression	
  
          and	
   processing	
   of	
   sterol	
   regulatory	
   element	
   binding	
   proteins,	
   thereby	
   increasing	
   the	
  
          expression	
  of	
  their	
  target	
  genes.	
  FEBS	
  J	
  278,	
  2739-­-2750.	
  

     105. Xia,	
   M.,	
   Liu,	
   Y.,	
   Guo,	
   H.	
   y	
   col.	
   2013.	
   Retinol	
   binding	
   protein	
   4	
   stimulates	
   hepatic	
  
          sterol	
   regulatory	
   element-­-binding	
   protein	
   1	
   and	
   increases	
   lipogenesis	
   through	
   the	
  
          peroxisome	
   proliferator-­-activated	
   receptor-­-?	
   coactivator	
   1ß-­-dependent	
   pathway.	
  
          Hepatology	
  58,	
  564-­-575.	
  

     106. Zhang,	
  Y.,	
  Lei,	
  T.,	
  Huang,	
  J.F.	
  y	
  col.	
  2011.	
  The	
  link	
  between	
  fibroblast	
  growth	
  factor	
  
          21	
   and	
   sterol	
   regulatory	
   element	
   binding	
   protein	
   1c	
   during	
   lipogenesis	
   in	
   hepatocytes.	
  
          Mol	
  Cell	
  Endocrinol	
  342,	
  41-­-47.	
  

     107. Ruderman,	
  N.B.,	
  Xu,	
  X.J.,	
  Nelson,	
  L.	
  y	
  col.	
  2010.	
  AMPK	
  and	
  SIRT1:	
  a	
  long-­-standing	
  
          partnership?	
  Am	
  J	
  Physiol	
  Endocrinol	
  Metab	
  298,	
  E751-­-760.	
  

     108. Bécard,	
   D.,	
   Hainault,	
   I.,	
   Azzout-­-Marniche,	
   D.	
   y	
   col.	
   2001.	
   Adenovirus-­-mediated	
  
          overexpression	
   of	
   sterol	
   regulatory	
   element	
   binding	
   protein-­-1c	
   mimics	
   insulin	
   effects	
   on	
  
          hepatic	
   gene	
   expression	
   and	
   glucose	
   homeostasis	
   in	
   diabetic	
   mice.	
   Diabetes	
   50,	
   2425-­-
          2430.	
  

     109. Lemoine,	
   M.,	
   Barbu,	
   V.,	
   Girard,	
   P.M.	
   y	
   col.	
   2006.	
   Altered	
   hepatic	
   expression	
   of	
  
          SREBP-­-1	
   and	
   PPARgamma	
   is	
   associated	
   with	
   liver	
   injury	
   in	
   insulin-­-resistant	
  
          lipodystrophic	
  HIV-­-infected	
  patients.	
  AIDS	
  20,	
  387-­-395.	
  

     110. Eberlé,	
   D.,	
   Clément,	
   K.,	
   Meyre,	
   D.	
   y	
   col.	
   2004.	
   SREBF-­-1	
   gene	
   polymorphisms	
   are	
  
          associated	
  with	
  obesity	
  and	
  type	
  2	
  diabetes	
  in	
  French	
  obese	
  and	
  diabetic	
  cohorts.	
  Diabetes	
  
          53,	
  2153-­-2157.	
  

     111. Biddinger,	
   S.B.,	
   Almind,	
   K.,	
   Miyazaki,	
   M.	
   y	
   col.	
   2005.	
   Effects	
   of	
   diet	
   and	
   genetic	
  
          background	
   on	
   sterol	
   regulatory	
   element-­-binding	
   protein-­-1c,	
   stearoyl-­-CoA	
   desaturase	
   1,	
  
          and	
  the	
  development	
  of	
  the	
  metabolic	
  syndrome.	
  Diabetes	
  54,	
  1314-­-1323.	
  

     112. Teran-­-Garcia,	
   M.,	
   Adamson,	
   A.W.,	
   Yu,	
   G.	
   y	
   col.	
   2007.	
   Polyunsaturated	
   fatty	
   acid	
  
          suppression	
   of	
   fatty	
   acid	
   synthase	
   (FASN):	
   evidence	
   for	
   dietary	
   modulation	
   of	
   NF-­-Y	
  
          binding	
  to	
  the	
  Fasn	
  promoter	
  by	
  SREBP-­-1c.	
  Biochem	
  J	
  402,	
  591-­-600.	
  

     113. Leavens,	
  K.F.,	
  Easton,	
  R.M.,	
  Shulman,	
  G.I.	
  y	
  col.	
  2009.	
  Akt2	
  is	
  required	
  for	
  hepatic	
  
          lipid	
  accumulation	
  in	
  models	
  of	
  insulin	
  resistance.	
  Cell	
  Metab	
  10,	
  405-­-418.	
  

                                                                                                                               	
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