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218ANALESRANFwww.analesranf.comAn. R.Acad. Farm.Vol. 91. n%u00ba2 (2025) %u00b7 pp. 217-225KEYWORDSAnemiaFerricCarboxymaltoseBlood TransfusionPreoperative Care1. INTRODUCCI%u00d3NLa anemia preoperatoria es un problemaprevalente que afecta a una proporci%u00f3nsignificativa de pacientes sometidos a cirug%u00edasprogramadas, y se asocia con resultadoscl%u00ednicos negativos. La Organizaci%u00f3n Mundial dela Salud (OMS) define la anemia seg%u00fan umbralesespec%u00edficos de concentraci%u00f3n de Hb (Hb),estableciendo l%u00edmites de 13 g/dL para hombresy 120 g/dL para mujeres, mientras que enni%u00f1os menores de 5 a%u00f1os y mujeresembarazadas se considera anemia con Hb <11g/dL. Seg%u00fan la OMS, la anemia por deficienciade hierro (ADI) se define como niveles deferritina inferiores a 15 microgramos/L, conniveles de Hb por debajo de 12 g/dL paramujeres no embarazadas de 12 a%u00f1os o m%u00e1s ypor debajo de 13 g/dL para hombres de 15Iron carboxymaltose in preoperative anemiain surgical patients%u00c1ngel Manuel Yuste Guti%u00e9rreza%u00f1os o m%u00e1s. En el contexto preoperatorio, laanemia se ha vinculado a un mayor riesgo decomplicaciones durante y despu%u00e9s de lacirug%u00eda, as%u00ed como a la necesidad detransfusiones de sangre y a estanciashospitalarias prolongadas. La prevalencia dela anemia preoperatoria var%u00edaconsiderablemente seg%u00fan el tipo de cirug%u00eda,oscilando entre un 10% y un 70%, siendoparticularmente alta en intervencionesoncol%u00f3gicas y ginecol%u00f3gicas (1-4).La anemia preoperatoria es un factor deriesgo independiente para la transfusi%u00f3n desangre en el periodo perioperatorio y se asociacon un aumento en la morbilidad y mortalidadpostoperatoria (1,5). Las transfusiones degl%u00f3bulos rojos, aunque necesarias en algunoscasos, presentan riesgos a%u00f1adidos, comoinfecciones, sobrecarga circulatoria, eventosABSTRACTIntroduction: Preoperative anemia is a common and significant issue inpatients undergoing elective surgeries, which is associated with increasedcomplications, blood transfusion needs, and prolonged hospital stays.Anemia is defined by hemoglobin (Hb) levels below 13 g/dL for men and 120g/dL for women. Iron deficiency anemia (IDA) is a major cause ofpreoperative anemia, and intravenous (IV) iron, particularly ferriccarboxymaltose (FCM), has been suggested as an effective treatment tooptimize Hb levels. This study aims to assess the efficacy of FCMadministration in improving Hb levels in anemic patients during preoperativeanesthesia consultations.Material and methods: This retrospective cohort study included 213 adultpatients undergoing scheduled surgeries. The treatment group (n=103)received FCM during preoperative anesthesia consultations, while the controlgroup (n=110) did not receive treatment. The primary outcome was thechange in Hb levels between the anesthesia consultation and surgery.Results: The FCM group showed a significant increase in Hb levels, with anaverage increase of +0.63 g/dL, compared to a decrease of -0.33 g/dL in thecontrol group (p<0.001). Additionally, ferritin levels were significantly lowerin the treatment group compared to the control group.Discussion: The results suggest that FCM administration is an effectivemethod to improve Hb levels before surgery, especially in patients with irondeficiency. The significant improvements observed align with previousstudies and underscore the importance of optimizing Hb preoperatively.Conclusion: FCM administration during preoperative consultations iseffective in increasing Hb levels and reducing the need for transfusions,potentially improving perioperative outcomes.