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Conflict of interestsThe author declare no conflict of interest.AcknowledgmentPasteur Laboratorios for carrying out thelaboratory tests.Code of ethicsThe present research work was accepted andapproved by the ethics committee of PasteurLaboratories. On the other hand, the culturesare obtained from a routine sample,therefore, informed concentration is notnecessary.6. REFERENCES1. Kumar A., et al., Prediabetes, undiagnoseddiabetes, and diabetes among Mexicanadults: findings from the Mexican Health andAging Study., Annals of Epidemiology., 2016 26,163e170 https://doi.org/10.1016/j.annepidem.2015.12.0062. Banerjee A., et al., Role of Serum Adiponectinand Vitamin D in Prediabetes and DiabetesMellitus., Can J Diabetes., 2017, 41(3), 259-265.https://doi.org/10.1016/j.jcjd.2016.10.0063. Punthakee Z., et al., Definition, Classification andDiagnosis of Diabetes, Prediabetes and MetabolicSyndrome., Can J Diabetes., 2018, 42 S10-S15DOI:https://doi.org/10.1016/j.jcjd.2017.10.0034. Chou K., Molecular Therapeutic Target forType-2 Diabetes., J. Proteome Res. 2004, 3,1284-1288 doi: 10.1021/pr049849v5. Mishra S., et al., Diabetic foot., BMJ. 2017,359, j5064 Doi:10.1136/bmj.j50646. Zhang P., et al., Global epidemiology ofdiabetic foot ulceration: a systematic reviewand meta-analysis., Ann. Med., 2017, 47(2),106-116 doi:10.1080/07853890.2016.12319327. Noor S., et al., Understanding Diabetic FootInfection and its Management., DiabetesMetab. Syndr., 2017, 11(2), 149-156https://doi.org/10.1016/j.dsx.2016.06.0238. Saltoglu S., Ergonul O., Tulek N., et al.,Influence of multidrug resistant organisms onthe outcome of diabetic foot infection., IntJ Infect Dis., 2018,70, 10-14 doi:10.1016/j.ijid.2018.02.013.Furthermore, expanding the sample andincluding additional variables could provide adeeper understanding of the mechanismsunderlying oxacillin resistance.5. CONCLUSIONDiabetes mellitus, especially in low- andmiddle-income countries, is positioned as agrowing threat to global public health. Itsimpact on health systems is aggravated by theassociated complications, among whichdiabetic foot stands out. This study revealsworrying data: the prevalence of methicillinresistant Staphylococcus aureus (MRSA)infections in diabetic foot wounds reaches analarming 63% in the population studied.This scenario highlights the urgent need toimplement effective measures for infectioncontrol and the adequate administration ofantibiotics in diabetic patients, taking intoaccount that first and second line medicationsare compromised in a high percentage. Thestatistical analysis of the study addscomplexity to the picture: resistance tooxacillin does not depend solely on glycemiccontrol, high blood pressure, the number ofreinfections or gender. This is a multifactorialphenomenon that requires a broaderapproach, considering both clinical andmicrobiological factors.The high resistance observed to multipleclasses of antibiotics, including MLS-typeresistance and fluoroquinolones, raises alarmbells. It is imperative to develop more robuststrategies for the management of infections inpatients with diabetes mellitus. Our study has some limitations, such as thesample size, the lack of molecular studies todetect specific genes present in the isolatedstrains, among others. However, it shows aclear panorama that gives rise to more indepth studies.FinancingThis work did not receive funding support.496ANALESRANFwww.analesranf.comIdentificaci%u00f3n de Staphylococcus aureusy prevalencia de Staphylococcus aureus resistente a meticilina Jorge Almeida et al.An. R. Acad. Farm.Vol. 90. n%u00ba 4 (2024) %u00b7 pp. 489-498