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ultimately show resistance to methicillin (16).The high prevalence of strains of S. aureusresistant to methicillin in the community isincreasing, as shown in our study, where thepopulation evaluated is small and yet shows41 strains equivalent to 63% as resistant tomethicillin.Methicillin-resistant Staphylococcus aureus(MRSA) infection was associated with patientsin hospitals and skilled nursing facilities. Inrecent years, reports of community-associatedMRSA infections (CA-MRSA) have beenincreasing. Just 20 years ago in the UnitedStates, skin infections caused by methicillinresistant S. aureus were observed to increasefrom 29% in 2001 to 64% in 2004 (17).In a study carried out in 2014 by Lavery andcollaborators in the identification of bacteriain diabetic foot, it was shown the prevalenceof Staphylococcus aureus was 42.1%, and 70%of these isolates were methicillin resistant(18).In a study conducted by Lin Shin andcollaborators in 2020 in Miaoli, methicillinresistant Staphylococcus was found in 24.1% ofthe sample studied, but not a higherpercentage of methicillin-sensitiveStaphylococcus. In their study they realizedthat the consumption of oral hypoglycemicshowed only 33.8% (n=22) andtrimethoprim/sulfamethoxazole 23% (n=15),for linezolid and daptomycin alone 1.5% (n=1)showed resistance. Table 2 shows theresistance patterns to the antibiotics testedfor S. aureus and Graph No. 1 shows thepatterns of resistance and sensitivity to theantibiotics tested. Where a high resistance tobeta-lactams is seen, typical of resistance tomethicillin in some strains and in others aproduction of beta-lactamases. On the otherhand, it is important to highlight the high MLStype resistance present, with theerythromycin marker. For quinolones andtetracycline there is also a high resistance ofmore than 50%.4. DISCUSSIONStaphylococcus aureus is one of the mostimportant causes community acquiredpathogens. Antibiotic resistance is verycommon among strains of S. aureus. One ofthe most resistant forms of this bacterium ismethicillin-resistant strains (15). Methicillin isused to treat bacterial infections caused byorganisms of the genus Staphylococcus. It isactive against certain types of staphylococci,which are resistant to penicillin, but494ANALESRANFwww.analesranf.comIdentificaci%u00f3n de Staphylococcus aureusy prevalencia de Staphylococcus aureus resistente a meticilina Jorge Almeida et al.An. R. Acad. Farm.Vol. 90. n%u00ba 4 (2024) %u00b7 pp. 489-498Graph 1: Prevalence of Antibiotic Resistance in Staphylococcus aureus Isolated from Diabetic Foot Wounds