Page 60 - 87_02
P. 60
24. Karen Bush, Patrice Courvalin, Gautam Dantas, Julian Davies, Barry ANALES
Eisenstein, Pentti Huovinen, George A. Jacoby, Roy Kishon, Barry N.
Kreiswirth , Elizabeth Kutter, 2011. Tackling antibiotic resistance. RANF
BMJ (Clinical research ed.), 340(may18 2),.
www.analesranf.com
25. Kong, K., Schneper, L. , Mathee, K., 2010. Beta-lactam antibiotics:
from antibiosis to resistance and bacteriology. Apmis, 118(1), pp. 36. Poirel, L., Kampfer, P. , Nordmann, P., 2002. Chromosome-Encoded
1-36. Ambler Class A -Lactamase of Kluyvera georgiana, a Probable Pro-
genitor of a Subgroup of CTX-M Extended-Spectrum -Lactamases.
26. Livermore, D., 2004. Can better prescribing turn the tide of resist- Antimicrobial Agents and Chemotherapy, 46(12), pp. 4038-4040.
ance? Nature Reviews Microbiology, 2(1), pp. 73-78.
37. R. P. Ambler, 1980. The structure of ß-lactamases. The Royal
27. Luepke, K.H., Suda, K.J., Boucher, H., Russo, R.L., Bonney, M.W., Society.
Hunt, T.D. , Mohr, J.F., 2017. Past, Present, and Future of Antibac-
terial Economics: Increasing Bacterial Resistance, Limited Antibiotic 38. Risso, V.A., Gavira, J.A., Mejia-Carmona, D.F., Gaucher, E.A. ,
Pipeline, and Societal Implications. Pharmacotherapy: The Journal Sanchez-Ruiz, J.M., 2013. Hyperstability and Substrate Promiscuity
of Human Pharmacology and Drug Therapy, 37(1), pp. 71-84. in Laboratory Resurrections of Precambrian ß-Lactamases. Journal
of the American Chemical Society, 135(8), pp. 2899-2902.
28. Melise Chaves Silveira, Rangeline Azevedo Da Silva, FábioFaria Da
Mota, Marcos Catanho, Rodrigo Jardim, Ana Carolina,R. Guimarães, 39. Sambrook, J. , Green, M.R., 2012. Molecular cloning: a laboratory
Antonio B De Miranda, 2018. Systematic Identification and Classi- manual. 4th edn. United States: Cold Spring Harbor Laboratory Press.
fication of ß-Lactamases Based on Sequence Similarity Criteria: ß-
Lactamase Annotation. , pp. 1-11. 40. Siddiq, M.A., Hochberg, G.K. , Thornton, J.W., 2017. Evolution of
protein specificity: insights from ancestral protein reconstruction. Cur-
29. Meroueh, S.O., Minasov, G., Lee, W., Shoichet, B.K. , Mobashery, rent Opinion in Structural Biology, 47, pp. 113-122.
S., 2003. Structural Aspects for Evolution of ß-Lactamases from
Penicillin-Binding Proteins. Journal of the American Chemical Society, 41. Thierry Naas, Laurence Vandel, Wladimir Sougakoff, David M. Liv-
125(32), pp. 9612-9618. ermore , Patrice Nordmann`, 1994. Hydrolyzing Class A PLactamase,
Sme-1, from.
30. Neelanjana Pandey , Marco Cascella, 2019. Beta Lactam Antibiotics.
StatPearls, 20(10) pp. 20. 42. Thornton, J.W., 2004. Resurrecting ancient genes: experimental
analysis of extinct molecules. Nature Reviews Genetics, 5(5), pp.
31. Nicoletti, A.G., Marcondes, M.F.M., Martins, Willames M B S, 366-375.
Almeida, L.G.P., Nicolás, M.F., Vasconcelos, A.T.R., Oliveira, V. ,
Gales, A.C., 2015. Characterization of BKC-1 Class A Carbapenemase 43. Ur Rahman, S., Ali, T., Ali, I., Khan, N.A., Han, B. , Gao, J., 2018.
from Klebsiella pneumoniae Clinical Isolates in Brazil. Antimicrobial The Growing Genetic and Functional Diversity of Extended Spectrum
agents and chemotherapy, 59(9), pp. 5159-5164. Beta-Lactamases. BioMed research international, 2018, pp.
9519718-14.
32. Novais, A., Comas, I., Baquero, F., Cantón, R., Coque, T.M., Moya,
A., González-Candelas, F. , Galán, J., 2010. Evolutionary Trajectories 44. Usman Umar Zango, Munir Ibrahim, Sadiq Abdurrahman, Abubakar
of Beta-Lactamase CTX-M-1 Cluster Enzymes: Predicting Antibiotic Shawai , Ibrahim Muhammad Shamsuddin, 2019. A review on ß-
Resistance. PLoS pathogens, 6(1), pp. e1000735. lactam antibiotic drug resistance. MOJ Drug Des Develop Ther., pp.
52-58.
33. Arveen Salahuddin, Amit Kumar , Asad U. Khan, 2018. Structure,
Function of Serine and Metallo-ß-lactamases and their Inhibitors. 45. Vollmer, W., Blanot, D. , De Pedro, M.A., 2008. Peptidoglycan struc-
Current Protein & Peptide Science, 19(2), pp. 130-144. ture and architecture. FEMS Microbiology Reviews, 32(2), pp. 149-
167.
34. Pazos, M. , Peters, K., 2019. Peptidoglycan. Sub-cellular biochem-
istry, 92, pp. 127-168. 46. WHO, 2018. WHO Report on Surveillance of Antibiotic Consumption
47. Yigit, H., Queenan, A.M., Anderson, G.J., Domenech-Sanchez, A.,
35. Philippon, A., Slama, P., Dény, P. , Labia, R., 2016. A Structure-
Based Classification of Class A ß-Lactamases, a Broadly Diverse Biddle, J.W., Steward, C.D., Alberti, S., Bush, K. , Tenover, F.C., 2001.
Family of Enzymes. Clinical microbiology reviews, 29(1), pp. 29- Novel Carbapenem-Hydrolyzing ß-Lactamase, KPC-1, from a Car-
57. bapenem-Resistant Strain of Klebsiella pneumoniae. Antimicrobial
Agents and Chemotherapy, 45(4), pp. 1151-1161.
48. Zakas, P.M., Brown, H.C., Knight, K., Meeks, S.L., Spencer,
H.T.,Gaucher, E.A. , Doering, C.B., 2017. Enhancing the pharma-
ceutical properties of protein drugs by ancestral sequence reconstruc-
tion. Nature biotechnology, 35(1), pp. 35-37.
Ancestral reconstruction of a b-lactamase and comparison with
166 its extant proteins
Gonzalo Fernández Balaguer, Carmen Del Águila, Carolina Hurtado Marcos y Rubén Agudo Torres
An. Real Acad. Farm. Vol. 87. Nº 2 (2021) · pp. 155 - 170
