Page 108 - 78_04
P. 108
BORIS
GUZMÁN
FERNÁNDEZ
&
col
de
un
grupo
de
compuestos
analogos
del
acyclovir
y
ganciclovir.
An.
R.
Acad.
Nac.
Farm
76(1),
45--57.
30. Gálvez--Llompart
M.,
Recio
M.C.,
García--Domenech
R.
(2011)
Topological
virtual
screening:
a
way
to
find
new
compounds
active
in
ulcerative
colitis
by
inhibiting
NF--?B.
Mol
Divers
15(4),
917--26.
31. Casabán--Ros
E.,
Antón--Fos
G.M.,
Gálvez
J.,
et
al.
(1999)
Search
for
New
Antihistaminic
Compounds
by
Molecular
Connectivity.
Quant
Struct--Act
Relat
18,
35--42.
32. Jasinski
P.,
Welsh
B.,
Galvez
J.,
et
al.
(2008)
A
novel
quinoline,
MT477:
Suppresses
cell
signaling
through
ras
molecular
pathway,
inhibits
PKC
activity,
and
demonstrates
in
vivo
anti--tumor
activity
against
human
carcinoma
cell
lines.
Invest
New
Drugs
26(3),223--232.
33. Jasinski
P.,
Zwolak
P.,
Isaksson
V.R.,
et
al.
(2011)
MT103
inhibits
tumor
growth
with
minimal
toxicity
in
murine
model
of
lung
carcinoma
via
induction
of
apoptosis.
Invest
New
Drugs
29(5),1--7.
34. Galvez
J.,
Llompart
J.,
Land
D.,
et
al.
(2010)
Mount
Sinai
School
of
Medicine
of
New
York
University,
USA,
Medisyn
Technologies
I,
assignees.
Compositions
for
treatment
of
Alzheimer’s
disease
using
Abeta--reducing
and/or
Abeta--anti--aggregation
compounds.
WO/2010/114636;
PCT/US2010/001041.
35. Lutje
V.,
Seixas
J.,
Kennedy
A.(2010)
Chemoterapy
for
second--stage
Human
African
trypanosomiasis.
Cochrane
Database
of
Systematic
Reviews.
Issue
8.
Art.
No.:
CD006201.
DOI:10.1002/14651858.CD006201.
36. Bourdin
B.,
Jedrysiak
R.,
Tweats
D.,
Brun
R.,
Kaiser
M.,
Suwinski
J.,
Torreele
E.
(2011)1--
Aril--4--nitro--1H--imidazoles,
a
new
promising
series
for
the
treatment
of
human
African
trypanosomiasis.
Eur
J
Med
Chem
46,
1524--1535.
37. Randic,
M.
(1975)
On
characterization
of
molecular
branching.
J
Am
Chem
Soc
97,
6609--
6615.
38. Kier
L.B.,
Hall
L.H.
(1986)
Molecular
Connectivity
in
Structure--Activity
Analysis.
Research
Studies
Press,
Letchworth,
UK.
39. Gálvez
J.,
García--Doménech
R.,
Salabert
M.T.,
Soler
R.
(1994)
Charge
Indices.
New
topological
descriptors.
J
Chem
Inf
Comput
Sci
34,
520--525.
40. Statistica
(data
analysis
software
system),
version
9.0(2009)
Statsoft:
Tulsa,
OK.
41. Wold
S.,
Eriksson
L.,
Clementi
S.
(2008)
Statistical
validation
of
QSAR
results,
in
Chemometric
Methods
in
Molecular
Design
(ed
H.
van
de
Waterbeemd),
Wiley--VCH
Verlag
GmbH,
Weinheim,
Germany.
doi:
10.1002/9783527615452.ch5.
42. Dixon
W.J.
(1990)
BMDP
statistical
software
manual:
to
accompany
the
1990
software
release.
Univ
of
California
Pr;
San
Francisco.
43. Roy
P.P.,
Leonard
J.T.,
Roy
K.
(2008)
Exploring
the
impact
of
size
of
training
sets
for
the
development
of
predictive
QSAR
models.
Chem
Intell
Lab
Syst
90(1),
31--42.
44. Galvez
J.,
Garcia--Domenech
R.,
de
Gregorio
Alapont
C.,
et
al.
(1996)
Pharmacological
distribution
diagrams:
a
tool
for
de
novo
drug
design.
J
Mol
Graph
14(5),
272--276.
45. Lachenbruch
P.A.,
Mickey
M.R.
(1968)
Estimation
of
error
rates
in
discriminant
analysis.
Technometrics
10(1),
1--11.
526