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BORIS
GUZMÁN
FERNÁNDEZ
&
col

Tabla
3.-­-
Resultados
obtenidos
del
cribado
molecular
realizado
con
nuevos
derivados
del
4-­-nitro-­-
imidazol
utilizando
el
análisis
lineal
discriminante.

N0. R1 R2 R3 4?pc G2v J5 Prob.(A) FD Clascalc

1 CH3 H Ph 1.345 6.182 0.041 0.614 0.47 A
H H 1.577 6.720 0.042 0.755 1.13 A
Ph

2N

N

3 H H 1.677 4.515 0.045 0.998 5.99 A
H H 1.342 4.552 0.041 0.990 4.62 A
Cl F

4

5 H H 1.342 4.552 0.039 0.995 5.39 A
6H
7H H Ph 1.369 6.182 0.044 0.359 -0.57 I

S
CH3

H 1.879 7.747 0.031 0.997 5.70 A

O

OCH3

8 H H 1.374 4.390 0.064 0.012 -4.37 I

F F H H 1.543 4.182 0.055 0.788 1.31 A
Cl H H 1.625 4.850 0.069 0.004 -5.51 I
9 H 1.543 4.701 0.055 0.497 -0.01 I
Cl H 1.755 4.664 0.055 0.885 2.04 A
10 H 1.538 5.764 0.059 0.013 -4.36 I
H
Cl H 2.085 6.169 0.067 0.020 -3.87 I

11

Cl

F H
H
12

Cl
CH3

13

Br

14 CH3

522
O

CF3