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VOL. 76 (2), 259-305, 2010  UTILIZACIÓN DE HIDROLASAS EN LA PREPARACIÓN...

34. Nemoto, K., et al. (1987) Effect of 15-deoxyspergualin on graft-v-host disease
       in mice. Trans. Proc. 19(5): 3985.

35. Mahmoudian, M.; Eaddy, J. & Dawson, M. (1999) Enzymic acylation of
       506U78 (2-amino-9-ß-D-arabinofuranosyl-6-methoxy-9H-purine), a powerful
       new anti-leukaemic agent. Biotechnol. Appl. Biochem. 2: 229-233.

36. Ondetti, M. A. & Cushman, D. W. (1981) Inhibition of rennin-angiotensin
       system: a new approach of the theory of hypertension. J. Med. Chem. 24: 355.

37. Ondetri, M. A., et al. (1977) Design of specific inhibitors of angiotensin con-
       verting enzyme: new class of orally active antihypertensive agents. Science.
       196: 441.

38. Cushman, D. W. & Ondetti, M. A. (1980) Inhibitors of angiotensin-converting
       enzyme for treatment of hypertension. Biochem. Pharm. 29: 1871.

39. Goodhue, C. T. & Schaeffer, J. R. (1971) Preparation of L-(+)- $- hydroxibu-
       tyric acid by bacterial oxidation of isobutyric acid. Biotechnol. Bioeng. 13: 203.

40. Patel, R. N., et al. (1992) Stereoselective enzymalic hydrolysis of “-[acetil-
       thi)methyl]benzenepropanoic acid and 3-acetylthio-2-methylpropanoic acid.
       Biotechnol. Appl. Biochem. 16: 34.

41. Patel, R. N., et al. (1991) Stereoselective enzymatic esterification of 3-ben-
       zoylthio-2-methylpropanoic acid. Appl. Microbiol. Biotechnol. 36: 29.

42. Moniot, J. L. (1988) Preparation of N-{2-(mercaptomethyl)propyonyl]-L-proli-
       nes, U.S. Patent Appl. CN88-100862.

43. Ondetti, M. A.; Miguel, A. & Krapcho, J. (1982) Mercaptoacyl derivatives of
       substituted prolines, LS. Patent, 4316906.

44. Patel, R. N.; Robison, R. S. & Szarka, L. J. (1990) Stereoselective enzymic
       hydrolysis of 2-cyclohexyl- and 2-phenyl-1,3-propancdiol diacetate in biphasic
       systems. Appl. Microbiol. Biotechnol. 34: 10.

45. Hanson, R. L., et al. (1992) Transformation of N-, -CBZ-L-lysine to CBZ-L-
       oxylysine using L-amino acid oxidase froni Providencia a1califaciens and L-2-
       hydroxy-isocaproate dehydrogenase from Lactobacilus confusus. Appl. Micra-
       biol. Biotechnol. 37: 599.

46. Hulshof, L. A. & Roskam, J. H. (1989) Phennykglycidate stereoisomers, con-
       version products thereof with e.g. 2-nitrophenol and preparation of diltiazem.
       European Patent EP0343714. (Chem. Abstr. 113, 76603).

47. Matsumae, H.; Furui, M. & Shibatani, T. (1993) Lipase catalyzed asymmetric
       hydrolysis of 3-phenylglycidic acid ester, the key intermediate in the synthesis
       of diltiazem hydrochloride. J. Ferm. Bioeng. 75: 93.

48. Matsumae, H.; Furui, M.; Shibatani, T. & Tosa, T. (1994) Production of op-
       tically active 3-phenylglicidic acid ester by the lipase from Serratia marcescens
       on a hollow-fiber membrane reactor. J. Ferment. Bioeng. 78: 59.

49. Furui, M.; Furutani, T.; Shibatani, T.; Nakamoto, Y., Mori, T. H. (1996) A
       membrane bioreator combined with cristallizer for production of optically
       active (2R,3S)-3-(4-metoxifenil) glycidic acid methyl ester. J. Ferm. Bioeng.
       81: 21.

50. Fishman, A., et al. (2001) Enzymatic resolution as a convenient method for
       the production of chiral resolved rnaterials on an industrial scale. Biotechnol.
       Bioeng. 74: 256.

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