Page 48 - 74_02

ANA I. GUZMÁN-ARÁNGUEZ Y COLS. AN. R. ACAD. NAC. FARM.

BIBLIOGRAFÍA

(1) ROACH, H. I.; ERENPREISA, J. and AIGNER, T. (1995): Osteogenic differentiation
(2) of hypertrophic chondrocytes involves asymmetric cell divisions and apopto-
(3) sis. J. Cell Biol. 131: 483-494.
(4) GIBSON, G.; LIN, D. L. and ROQUE, M. (1997): Apoptosis of terminally differen-
tiated chondrocytes in culture. Exp. Cell Res. 233: 372-382.
(5) ANON, J. (1988): Human achondroplasia. A multidisciplinary approach. Pro-
ceeding of the first international symposium. November 19-21, Rome, Italy.
(6) Basic Life Sci. 48: 1-419.
SHIANG, R.; THOMPSON, L. M.; ZHU, Y. Z.; CHURCH, D. M.; FIELDER, T. J.; BOCIAN,
(7) M.; WINOKUR, S. T. and WASMUTH, J. J. (1994): Mutations in the transmembra-
(8) ne domain of FGFR3 cause the most common genetic form of dwarfism,
(9) achondroplasia. Cell. 78: 335-342.
ROUSSEAU, F.; BONAVENTURE, J.; LEGEAI-MALLET, L.; PELET, A.; ROZET, J. M.; MA-
(10) ROTEAUX, P.; LE MERRER, M. and MUNNICH, A. (1994): Mutations in the gene
(11) encoding fibroblast growth factor receptor-3 in achondroplasia. Nature. 371:
252-254.
(12) SUPERTI-FURGA, A.; EICH, G.; BUCHER, H. U.; WISSER, J.; GIEDION, A.; GITZELMANN,
R. and STEINMANN, B. (1995): A glycine 375-to-cysteine substitution in the
(13) transmembrane domain of the fibroblast growth factor receptor-3 in a new-
born with achondroplasia. Eur. J. Pediatr. 154: 215-219.
CHEN, L.; ADAR, R.; YANG, X.; MONSONEGO, E. O.; LI, C.; HAUSCHKA, P. V.; YAYON,
A. and DENG, C. X. (1996): Receptor specificity of the fibroblast growth factor
family. J. Biol. Chem. 271: 15292-15297.
PRINOS, P.; COSTA, T.; SOMMER, A.; KILPATRICK, M. W. and TSIPOURAS, P. (1995):
A common FGFR3 gene mutation in hypochondroplasia. Hum. Mol. Genet. 4:
2097-2101.
IWATA, T.; CHEN, L.; LI, C.; OVCHINNIKOV, D. A.; BEHRINGER, R. R.; FRANCOMANO,
C. A. and DENG, C. X. (2000): A neonatal lethal mutation in FGFR3 uncouples
proliferation and differentiation of growth plate chondrocytes in embryos.
Hum. Mol. Genet. 9: 1603-1613.
COLVIN, J. S.; BOHNE, B. A.; HARDINNG, G. W.; MCEWEN, D. G. and ORNITZ, D.
M. (1996): Skeletal overgrowth and deafness in mice lacking fibroblast growth
factor receptor 3. Nat. Genet. 12: 390-397.
SCHLESSINGER, J.; PLOTNIKOV, A. N.; IBRAHIMI, O. A.; ELISEENKOVA, A. V.; YEH, B.
K.; YAYON, A.; LINHARDT, R. J. and MOHAMMADI, M. (2000): Crystal structure of
a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR
binding and dimerization. Mol. Cell. 6: 743-750.
HART, K. C.; ROBERTSON, S. C. and DONOGHUE, D. J. (2001): Identification of
tyrosine residues in constitutively activated fibroblast growth factor receptor
3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase
activation. Mol. Biol. Cell. 12: 931-942.
NASKI, M. C.; WANG, Q.; XU, J. and ORNITZ, D. M. (1996): Graded activation of
fibroblast growth factor receptor 3 by mutations causing achondroplasia and
thanatophoric dysplasia. Nat. Genet. 13: 233-237.

226