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VOL. 71 (1), 45-82, 2005 VÍA DE LA UBIQUITINA-PROTEOSOMA

(28) GLOTZER, M.; MURRAY, A. W. & KIRSCHNER, M. W. (1991). Cyclin is degraded
(29) by the ubiquitin pathway. Nature 349, 132-138.
(30) WEI, W.; AYAD, N. G.; WAN, Y.; ZHANG, G. J.; KRISCHNER, M. W. & KAELIN, W.
(31) G. (2004). Degradation of the SCF component Skp2 in cell cycle phase G1 by
(32) the anaphase promoting complex. Nature 428, 194-198.
(33) SUN, X. M. M.; BUTTERWORTH, M.; MACFARLANE, M.; DUBIEL, W.; CIECHANOVER, A.
(34) & COHEN, G. M. (2004). Caspase activation inhibits proteasome function du-
(35) ring apoptosis. Mol Cell. 14, 81-93.
(36) CASCALES, M. (2003). Bases Moleculares de la Apoptosis. Anal Real Acad Nac
(37) Farm 69, 43-70.
CHEN, F.; CHANG, D.; GOH, M.; KLIBANOV, S. A. & LJUNGMAN, M. (2000). Role of
(38) p53 in cell cycle regulation and apoptosis following exposute to proteosome
(39) ihibitors. Cell Growth Differ 11, 239-246.
(40) MACFARLANE, M.; MERRISON, W.; BRATTON, S. B.; COHEN, G. M. (2002). Protea-
some-mediated degradation of Smac during apoptosis: XIAP promotes Smac
(41) ubiquitination in vitro. J Biol Chem 277, 36611-36616.
CASCALES, M. (2002). Proteínas del estrés y carabinas moleculares. Proyeccio-
(42) nes clínicas y terapéuticas. Real Acad Nac Farm Madrid, pp. 72-77.
KIM, D.; KIM, S-H.; LI, G. C. (1999). Proteasome inhibitors MG-132 and lac-
tacystin hyperphosphorylate HSF1 and induce hsp70 and hsp27 expression.
Biochem Biophys Res Commun 254, 264-268.
YERLICAYA, A. (2004). Cellular functions of the 26S proteosome. Turk J Biol
28, 31-38.
MIMNAUGH, E. G.; XU, W.; VOS, M.; YUAN, X.; ISAACS, J. S.; BIST, K. S.; GIUS, D.
& NECKERS, L. (2004). Simultaneous inhibition of hsp90 and the proteoso-
me promotes protein ubiquitination, causes endoplasmic reticulum-derived
cytosol vacuolization and enhances antitumor activity. Mol Cancer Ther 3,
551-566.
MURATANI, M.; TANSEY, W. P. (2003). How the ubiquitin-proteasome system
controls transcription. Nat Rev Mol Cell Biol. 4, 192-201.
JESENBERGER, V.; JENTSCH, S. (2002). Deadly encounter: ubiquitin meets apop-
tosis. Nat Rev Mol Cell Biol. 3, 112-121.
BREITSCHOPF, K.; BENGAL, E.; ZIV, T.; ADMON, A. & CIECHANOVER, A. (1998). A
Novel Site for Ubiquitination: The N-Terminal Residue and Not Internal
Lysines of MyoD is Essential for Conjugation and Degradation of the Protein.
EMBO J. 17, 5964-5973.
ORIAN, A.; GONEN, H.; BERCOVICH, B.; FAJERMAN, I.; EYTAN, E.; ISRAEL, A.; MER-
CURIO, F.; IWAI, K.; SCHWARTZ, A. L. & CIECHANOVER, A. (2000). SCF-(beta)
(-TrCP) Ubiquitin Ligase-Mediated Processing of NF-kappaB p105 Requires
Phosphorylation of its C-Terminus by IkappaB Kinase. EMBO J. 19, 2580-
2591.
COHEN, S.; ORIAN, A. & CIECHANOVER, A. (2001). Processing of p105 is Inhibited
by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and In-
hibition is Alleviated by Signaling via the C-Terminal Phosphorylation/Ubi-
quitin-Ligase Binding Domain. J. Biol. Chem. 276, 26769-26776.

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