Page 84 - Demo

aemps/ultimainformacion-de-la-aemps-acercadel-covid%E2%80%9119/vacunas-contra-la-covid%E2%80%9119/comirnaty/.26. Ficha T%u00e9cnica Moderna vacuna Covid-19. AgenciaEspa%u00f1ola de Medicamentos y Productos Sanitarios(Internet). Madrid: Agencia Espa%u00f1ola deMedicamentos y Productos Sanitarios; (citado el1 de febrero de 2024). Disponible en:https://www.aemps.gob.es/la-aemps/ultimainformacion-de-la-aemps-acer-ca-del-covid%E2%80%9119/vacunas-contra-lacovid%E2%80%9119/covid-19-vaccine-moderna/.27. Eygeris Y, Gupta M, Kim J, Sahay G. Chemistry ofLipid Nanoparticles for RNA Delivery. Acc ChemRes. 2022;55(1):2-12.https://doi.org/10.1021/acs.accounts.1c00544.28. Genotipia. Pfizer vacuna covid (Internet). Genotipia;(citado el 3 de enero de 2024). Disponible en:https://genotipia.com/pfizer-vacuna-covid/.29. Karik%u00f3 K, Muramatsu H, Welsh FA, Ludwig J, Kato H,Akira S, et al. Incorporation of pseudouridine intomRNA yields superior nonimmunogenic vectorwith increased translational capacity andbiological stability. Mol Ther 2008;16(11):1833-40. https://doi.org/10.1038/mt.2008.200.30. Durbin AF,%u00a0Wang C,%u00a0Marcotrigiano J,%u00a0Gehrke L. %u00a0RNAsContaining Modified Nucleotides Fail To TriggerRIG-I Conformational Changes for Innate ImmuneSignaling. mBio. 2016;7(5):e00833-16.https://doi.org/ 10.1128/mBio.00833-16.31. Svitkin YV, Cheng YN, Chakraborty T, Presnyak V,John M, Sonenberg N et al. N1-methylpseudouridine in mRNA enhances translationthrough eIF2%u03b1-dependent and independentmechanisms by increasing ribosome density.Nucleic Acids Res. 2017;45(10):6023-36.https://doi.org/10.1093/nar/gkx135.32. L%u00f3pez-Sampalo A,%u00a0 Bernal-L%u00f3pez MR,%u00a0 G%u00f3mezHuelgasa R. S%u00edndrome de COVID-19 persistente.Una revisi%u00f3n narrative. Rev Clin Esp. 2022;222(4): 241-50.https://doi.org/10.1016/j.rce.2021.10.003.33. Quo, El Diario (Internet). El Diario; (citado el 2 defebrero de 2024). Disponible en:https://quo.eldiario.es/salud/coronavirus.238ANALESRANFwww.analesranf.comThe mRNA COVID 19 vaccine: More than a drug?Fernando Rius Alarc%u00f3An. R. Acad. Farm.Vol. 90. n%u00ba 2 (2024) %u00b7 pp. 215-238 Si desea citar nuestro art%u00edculo:La vacuna ARNm COVID 19: %u00bfm%u00e1s que unmedicamento? Fernando Rius Alarc%u00f3An Real Acad Farm (Internet).An. Real Acad. Farm.Vol. 90. n%u00ba 2 (2024) %u00b7 pp. 215-238DOI:http://dx.doi.org/10.53519/analesranf.2024.90.02.05