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180. Buckland, K.F., T.J. Williams, and D.M. Conroy, Histamineinduces cytoskeletal changes in human eosinophils viathe H(4) receptor. Br J Pharmacol, 2003. 140(6):p.1117-27, DOI: 10.1038/sj.bjp.0705530.181. Lim, H.D., et al., Evaluation of histamine H1-, H2-, andH3-receptor ligands at the human histamine H4receptor: identification of 4-methylhistamine as thefirst potent and selective H4 receptor agonist. JPharmacol Exp Ther, 2005. 314(3): p. 1310-21, DOI:10.1124/jpet.105.087965.182. Zhao, Y.X., et al., Stimulation of histamine H4 receptorparticipates in cold-induced browning of subcutaneouswhite adipose tissue. Am J Physiol Endocrinol Metab,2019, DOI: 10.1152/ajpendo.00131.2019.Nature, 1995. 377(6549): p. 527-9, DOI:10.1038/377527a0.167. Cui, J., et al., Macrophage migration inhibitory factorpromotes cardiac stem cell proliferation andendothelial differentiation through the activation ofthe PI3K/Akt/mTOR and AMPK pathways. Int J MolMed, 2016. 37(5): p. 1299-309, DOI:10.3892/ijmm.2016.2542.168. Okamatsu-Ogura, Y., et al., Possible involvement ofuncoupling protein 1 in appetite control by leptin. ExpBiol Med (Maywood), 2011. 236(11): p. 1274-81, DOI:10.1258/ebm.2011.011143.169. Monteleone, P., et al., Pronounced early increase incirculating leptin predicts a lower weight gain duringclozapine treatment. J Clin Psychopharmacol, 2002.22(4):p. 424-6.170. Arruda, A.P., et al., Low-grade hypothalamicinflammation leads to defective thermogenesis,insulin resistance, and impaired insulin secretion.Endocrinology, 2011. 152(4): p. 1314-26, DOI:10.1210/en.2010-0659.171. Kristof, E., et al., Clozapine modifies the differentiationprogram of human adipocytes inducing browning.Transl Psychiatry, 2016. 6(11): p. e963, DOI:10.1038/tp.2016.230.172. Elman, I., et al., Effects of risperidone on the peripheralnoradrenegic system in patients with schizophrenia: acomparison with clozapine and placebo.Neuropsychopharmacology, 2002. 27(2): p. 293-300,DOI: 10.1016/S0893- 133X(02)00314-7.173. Dwivedi, Y., H.S. Rizavi, and G.N. Pandey, Differentialeffects of haloperidol and clozapine on ((3)H)cAMPbinding, protein kinase A (PKA) activity, and mRNA andprotein expression of selective regulatory andcatalytic subunit isoforms of PKA in rat brain. JPharmacol Exp Ther, 2002. 301(1): p. 197-209, DOI:10.1124/jpet.301.1.197.174. Crane, J.D., et al., Inhibiting peripheral serotoninsynthesis reduces obesity and metabolic dysfunctionby promoting brown adipose tissue thermogenesis. NatMed, 2015. 21(2): p. 166-72, DOI: 10.1038/nm.3766.175. Oh, C.M., et al., Regulation of systemic energyhomeostasis by serotonin in adipose tissues. NatCommun, 2015. 6: p. 6794, DOI:10.1038/ncomms7794.176. Kim, H.J., et al., Metabolomic analysis of livers andserum from high-fat diet induced obese mice. JProteome Res, 2011. 10(2): p. 722-31, DOI:10.1021/pr100892r.177. Kwak, S.H., et al., Association of variations in TPH1 andHTR2B with gestational weight gain and measures ofobesity. Obesity (Silver Spring), 2012. 20(1): p. 233-8,DOI: 10.1038/oby.2011.253.178. Klepac, K., et al., The Gq signalling pathway inhibitsbrown and beige adipose tissue. Nat Commun, 2016.7: p. 10895, DOI: 10.1038/ncomms10895.179. Correll, C.U., From receptor pharmacology to improvedoutcomes: individualising the selection, dosing, andswitching of antipsychotics. Eur Psychiatry, 2010. 25Suppl 2: p. S12-21, DOI: 10.1016/S0924-9338(10)71701-6.44ANALESRANFwww.analesranf.comSecond-generation antipsychotic drugs and their impact onadipose tissuePatricia Rada, V%u00edtor Ferreira y %u00c1ngela M. ValverdeAn. R. Acad. Farm.Vol. 90. n%u00ba 1 (2024) %u00b7 pp. 21-44Si desea citar nuestro art%u00edculo:F%u00e1rmacos antipsic%u00f3ticos de segunda generaci%u00f3n y su impacto en el tejido adiposoPatricia Rada, V%u00edtor Ferreira y %u00c1ngela M. ValverdeAn Real Acad Farm (Internet).An. Real Acad. Farm.Vol. 90. n%u00ba 1 (2024) %u00b7 pp. 21-44DOI: http://dx.doi.org/10.53519/analesranf.2024.90.01.02