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ANALES Ranade AA, Liberles SD & patapoutian A. Piezo2 senses airway
RANF stretch and mediates lung inflation-inducede apnoea. Nature 2017;
541:176-181.
www.analesranf.com 31. Beech DJ & Xiao B. Piezo channel mechanisms in health and disease.
J Physiol. 2018; 596:965-967.
King D & Julius D. Spider toxins activate the capsaicin receptor to 32. Starowicz K & Finn DP. Cannabinoids and Pain: Sites and Mecha-
produce inflammation pain. Nature. 2006; 444:208-212. nisms of Action. Adv Pharmacol. 2017; 80:437-475.
14. Bohlen CJ & Julius D. Receptor-targeting mechanisms of pain-cau-
sing toxins: How ow? Toxicon.2012;60:254-264. Si desea citar nuestro artículo:
15. Dubin AE & Patapoutian A. Nociceptors: the sensors of the pain path- María Teresa Vilalba Díaz
way. J Clin Invest. 2010; 120:3760-3772.
16. Zhao J, King JV, Paulsen C, Cheng Y & Julius D. Irritant-evoked ac- Receptores para la temperatura y el tacto: sensores para
tivation and calcium modulation of the TRPA1 receptor. Nature sentir e interpretar el mundo que nos rodea. Premio Nobel
2020; 585: 141-145.
17. Bandell M, Mcpherson LJ & Patapoutian A. From chills to chilis: me- de Fisiología o Medicina 2021
chanisms for thermosensation and chemesthesis via thermoTRPs. An. Real Acad. Farm. [Internet].
Curr Opin Neurobiol. 2007; 17:490-497.
18. Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky An. Real Acad. Farm. Vol. 87. Nº 4 (2021) · pp. 447-457
CL, Jordt S-E & Julius D. The mentol receptor TRPM8 is the principal DOI: http://
detector of environmental cold. Nature 2007; 448:204-208.
19. McKemy DD, Neuhausser WM & Julius D. Identification of a cold re-
ceptor reveals a general role for TRP channels in thermosensation.
Nature. 2002; 416:52-58.
20. Venkatachalam K & Montell C. TRP channels. Annu Rev Biochem.
2007; 76:387-417.
21. Basmaum AI, Bautista DM, Scherrer GS & Julius D. Cellular and mo-
lecular mechanisms of pain. Cell. 2009; 139:267-284.
22. Patapoutian A, Tate S & woolf CJ. Transient receptor potential chan-
nels: targeting pain at the source. Nature Reviews 2009; 8: 55-68.
23. Liao M, Cao E, Julius D & Cheng Y. Structure of the TRPV1 ion chan-
nel determined by electron cryo-microscopy. Nature 2013; 504;107-
112.
24. Clapham DE. TRP channels as cellular sensors. Nature 2003;
426:517-524.
25. Woo S-H, Ranade S, Weyer AD, Dubin AE, Baba Y, Qiu Z, Petrus M,
Miyamoto T, Reddy K, Lumpkin EA, Stucky CL & Patapoutian A.
Piezo2 is required for Merkel-cell mechanotransduction. Nature.
2014; 509:622-626.
26. Woo A-H, Lukacs V, Nooij J C, Zaytseva D, Criddle CR, Francisco A,
Jesselll TM, Wilkinson KA & Patapoutian A.
27. Kefauver JM, Ward AB, Patapoutian A. Discoveries in structure and
physiology of mechanically activated ion channels. Nature 2020;
587:567-575.
28. Saotome K, Murthy SE, Kefauver JM, Whitwam T, Patapoutian A &
Ward AB. Structure of the mechanically activated ion channel Piezo1.
Nature 2018; 554:481-486.
29. Hof T, Chaigne S, Récalde A, Sallé L, Brette F & Guinamard R. Tran-
sient receptor potential channels in cardiac health and disease. Na-
ture Reviews. 2019; 16:344-360.
10. Buck LB, Jacks T, Julius D, Lehmann R, Marks AR, Robertson EJ&
Taniguchi T
30. Nonomura K, Woo S-H, Chang RB, Gillich A, Qiu Z, Francisco AG,

Receptores para la temperatura y el tacto: sensores para sentir e interpretar

457el mundo que nos rodea. Premio Nobel de Fisiología o Medicina 2021
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