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UPLC/ Tandem mass and antimicrobial activity of Khaya senegalensis (A.Juss.)

Table (2): The antibacterial and antifungal activities of Khaya acetone extract

Inhibition zone ( mm) MIC(µg/disc)
= 50
(% inhibition)

Microorganism KAE * Reference drug

Bacillus cereus a 100µg/disc 100µg/disc
19 ± 0.57* f 30 ±0.81 d

(21%) (33%)

Staphylococcus aureus a 19.66 ±1.20* g 30 ±0.34d = 50
(21%) (33%)

Salmonella typhimuriumb 15 ± 1.15 15 ±0.47 d = 25
(16%) (16%)

Escherichia coli b 20 ± 0.57* h 15 ± 0.40d = 25
(22%) (16%)

Pseudomonas aeruginosa b 17 ± 0.57* i 20 ± 0.42 d = 25
(18%) (22%)

Candida albicans c 25 ±1.15*j 40 ± 0.33e = 25
(27%) (44%)

* Khaya acetone extract, Each value is mean of three replication of experiment ± SE Values between brackets are the % inhibition
compared to control.

a: gram positive bacteria b: gram negative bacteria c: fungus d: Cephradine e: Ketoconazole

Unshared superscript letters between groups are the significant values at ( f: P = 0.0001, g: P = 0.0023, h:P = 0.0053, i: P = 0.0147. j: P =
0.0005)

*: Highly significant (P<0.01

@Real Academia Nacional de Farmacia. Spain 265