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The	
  role	
  of	
  the	
  catecholaminergic…	
  

	
  

     (9)	
   Akiva	
   P;	
   Toporik	
   A;	
   Edelheit	
   S;	
   et	
   al.	
   Transcription-­-mediated	
   gene	
   fusion	
   in	
   the	
   human	
  
             genome.	
  Genome	
  research	
  16:	
  30-­-36	
  (2006).	
  

     (10)	
   Kim	
  N;	
  Kim	
  P;	
  Nam	
  S;	
  Shin	
  S;	
  Lee	
  S.	
  	
  ChimerDB-­--­-a	
  knowledgebase	
  for	
  fusion	
  sequences.	
  
             Nucleic	
  acids	
  research	
  34:	
  D21-­-24	
  (2006).	
  

     (11)	
   Parra	
   G;	
   Reymond	
   A;	
   Dabbouseh	
   N;	
   et	
   al.	
   Tandem	
   chimerism	
   as	
   a	
   means	
   to	
   increase	
  
             protein	
  complexity	
  in	
  the	
  human	
  genome.	
  Genome	
  research	
  16:	
  37-­-44	
  (2006).	
  

     (12)	
   Buckingham	
  M;	
  Meilhac	
  S;	
  Zaffran	
  S.	
  	
  Building	
  the	
  mammalian	
  heart	
  from	
  two	
  sources	
  of	
  
             myocardial	
  cells.	
  Nature	
  reviews	
  6:	
  826-­-835	
  (2005).	
  

     (13)	
   Lopez-­-Sanchez	
   C;	
   Bartulos	
   O;	
   Martinez-­-Campos	
   E;	
   et	
   al.	
   Tyrosine	
   hydroxylase	
   is	
  
             expressed	
   during	
   early	
   heart	
   development	
   and	
   is	
   required	
   for	
   cardiac	
   chamber	
  
             formation.	
  Cardiovascular	
  research	
  88:	
  111-­-120	
  (2010).	
  

     (14)	
   Brand	
   T.	
   	
   Heart	
   development:	
   molecular	
   insights	
   into	
   cardiac	
   specification	
   and	
   early	
  
             morphogenesis.	
  Developmental	
  biology	
  258:	
  1-­-19	
  (2003).	
  	
  

     (15)	
   Chapman	
  SC;	
  Schubert	
  FR;	
  Schoenwolf	
  GC;	
  Lumsden	
  A.	
  	
  Anterior	
  identity	
  is	
  established	
  
             in	
   chick	
   epiblast	
   by	
   hypoblast	
   and	
   anterior	
   definitive	
   endoderm.	
   Development	
  
             (Cambridge,	
  England)	
  130:	
  5091-­-5101	
  (2003).	
  

     (16)	
   Hamburger	
   V;	
   Hamilton	
   HL.	
   A	
   series	
   of	
   normal	
   stages	
   in	
   the	
   development	
   of	
   the	
   chick	
  
             embryo.	
  Journal	
  of	
  Morphology	
  88:	
  43	
  (1951).	
  

     (17)	
   Takeuchi	
   JK,;Bruneau	
   BG.	
   	
   Directed	
   transdifferentiation	
   of	
   mouse	
   mesoderm	
   to	
   heart	
  
             tissue	
  by	
  defined	
  factors.	
  Nature	
  459:	
  708-­-711	
  (2009).	
  

     (18)	
   Oana	
  S;	
  Machida	
  S;	
  Hiratsuka	
  E;	
  et	
  al.	
  The	
  complete	
  sequence	
  and	
  expression	
  patterns	
  of	
  
             the	
   atrial	
   myosin	
   heavy	
   chain	
   in	
   the	
   developing	
   chick.	
   Biology	
   of	
   the	
   cell	
   /	
   under	
   the	
  
             auspices	
  of	
  the	
  European	
  Cell	
  Biology	
  Organization	
  90:	
  605-­-613	
  (1998).	
  

     (19)	
   Somi	
   S;	
   Klein	
   AT;	
   Houweling	
   AC;	
   et	
   al.	
   Atrial	
   and	
   ventricular	
   myosin	
   heavy-­-chain	
  
             expression	
  in	
  the	
  developing	
  chicken	
  heart:	
  strengths	
  and	
  limitations	
  of	
  non-­-radioactive	
  
             in	
  situ	
  hybridization.	
  J	
  Histochem	
  Cytochem	
  54:	
  649-­-664(2006).	
  	
  

     (20)	
   Yutzey	
   KE;	
   Rhee	
   JT;	
   Bader	
   D.	
   	
   Expression	
   of	
   the	
   atrial-­-specific	
   myosin	
   heavy	
   chain	
  
             AMHC1	
   and	
   the	
   establishment	
   of	
   anteroposterior	
   polarity	
   in	
   the	
   developing	
   chicken	
  
             heart.	
  Development	
  (Cambridge,	
  England)	
  120:	
  871-­-883	
  (1994).	
  

     (21)	
   Zhou	
   QY;	
   Quaife	
   CJ;	
   Palmiter	
   RD.	
   Targeted	
   disruption	
   of	
   the	
   tyrosine	
   hydroxylase	
   gene	
  
             reveals	
  that	
  catecholamines	
  are	
  required	
  for	
  mouse	
  fetal	
  development.	
  Nature	
  374:	
  640-­-
             643	
  (1995).	
  

     	
  
     	
  

    	
  

                                                                                                                            	
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