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P. 108

Papel	
  del	
  tejido	
  adiposo	
  blanco,	
  marrón	
  y	
  perivascular…	
  

	
  

     107. Hondares	
  E,	
  Rosell	
  M,	
  Gonzalez	
  FJ,	
  Giralt	
  M,	
  Iglesias	
  R,	
  Villarroya	
  F.	
  Hepatic	
  FGF21	
  
          expression	
  is	
  induced	
  at	
  birth	
  via	
  PPARalpha	
  in	
  response	
  to	
  milk	
  intake	
  and	
  contributes	
  to	
  
          thermogenic	
  activation	
  of	
  neonatal	
  brown	
  fat.	
  Cell	
  Metab.	
  2010;	
  11(3):206-­-12.	
  

     108. Nisoli	
   E,	
   Tonello	
   C,	
   Carruba	
   MO.	
   Nerve	
   growth	
   factor,	
   beta3-­-adrenoceptor	
   and	
  
           uncoupling	
   protein	
   1	
   expression	
   in	
   rat	
   brown	
   fat	
   during	
   postnatal	
   development.Neurosci	
  
           Lett.	
  1998;	
  246(1):5-­-8.	
  

     109. Nisoli	
   E,	
   Tonello	
   C,	
   Benarese	
   M,	
   Liberini	
   P,	
   Carruba	
   MO.	
   Expression	
   of	
   nerve	
  
           growth	
   factor	
   in	
   brown	
   adipose	
   tissue:	
   implications	
   for	
   thermogenesis	
   and	
   obesity.	
  
           Endocrinology	
  1996;	
  137(2):495-­-503.	
  	
  

     110. Néchad	
  M,	
  Ruka	
  E,	
  Thibault	
  J.	
  Production	
  of	
  nerve	
  growth	
  factor	
  by	
  brown	
  fat	
  in	
  
           culture:	
  relation	
  with	
  the	
  in	
  vivo	
  developmental	
  stage	
  of	
  the	
  tissue.	
  Comp	
  Biochem	
  Physiol	
  
           Comp	
  Physiol.	
  1994;	
  107(2):381-­-8.	
  

     111. Sornelli	
   F,	
   Fiore	
   M,	
   Chaldakov	
   GN,	
   Aloe	
   L.	
   Adipose	
   tissue-­-derived	
   nerve	
   growth	
  
           factor	
   and	
   brain-­-derived	
   neurotrophic	
   factor:	
   results	
   from	
   experimental	
   stress	
   and	
  
           diabetes.	
  Gen	
  Physiol	
  Biophys	
  2009;	
  28	
  Spec	
  No:179-­-83.	
  

     112. Tonello	
   C,	
   Giordano	
   A,	
   Cozzi	
   V,	
   Cinti	
   S,	
   Stock	
   MJ,	
   Carruba	
   MO,	
   et	
   al.	
   Role	
   of	
  
           sympathetic	
  activity	
  in	
  controlling	
  the	
  expression	
  of	
  vascular	
  endothelial	
  growth	
  factor	
  in	
  
           brown	
  fat	
  cells	
  of	
  lean	
  and	
  genetically	
  obese	
  rats.	
  FEBS	
  Lett.	
  1999;	
  442(2-­-3):167-­-72.	
  

     113. Kikuchi-­-Utsumi	
   K,	
   Gao	
   B,	
   Ohinata	
   H,	
   Hashimoto	
   M,	
   Yamamoto	
   N,	
   Kuroshima	
   A.	
  
           Enhanced	
   gene	
   expression	
   of	
   endothelial	
   nitric	
   oxide	
   synthase	
   in	
   brown	
   adipose	
   tissue	
  
           during	
  cold	
  exposure.	
  Am	
  J	
  Physiol	
  Regul	
  Integr	
  Comp	
  Physiol.	
  2002;	
  282(2):R623-­-6.	
  

     114. Fitzgibbons	
   TP,	
   Kogan	
   S,	
   Aouadi	
   M,	
   Hendricks	
   GM,	
   Straubhaar	
   J,	
   Czech	
   MP.	
  
           Similarity	
   of	
   mouse	
   perivascular	
   and	
   brown	
   adipose	
   tissues	
   and	
   their	
   resistance	
   to	
   diet-­-
           induced	
  inflammation.	
  Am	
  J	
  Physiol	
  Heart	
  Circ	
  Physiol	
  2011;	
  301(4):H1425-­-37.	
  

     115. Ortega	
  MT,	
  Xie	
  L,	
  Mora	
  S,	
  Chapes	
  SK.	
  Evaluation	
  of	
  macrophage	
  plasticity	
  in	
  brown	
  
           and	
  white	
  adipose	
  tissue.	
  Cell	
  Immunol	
  2011;	
  271(1):124-­-33.	
  

     116. Meijer	
   RI,	
   Serne	
   EH,	
   Smulders	
   YM,	
   van	
   Hinsbergh	
   VW,	
   Yudkin	
   JS,	
   Eringa	
   EC.	
  
           Perivascular	
  adipose	
  tissue	
  and	
  its	
  role	
  in	
  type	
  2	
  diabetes	
  and	
  cardiovascular	
  disease.	
  Curr	
  
           Diab	
  Rep.	
  2011;	
  11(3):211-­-7.	
  

     117. Police	
   SB,	
   Thatcher	
   SE,	
   Charnigo	
   R,	
   Daugherty	
   A,	
   Cassis	
   LA.	
   Obesity	
   promotes	
  
           inflammation	
   in	
   periaortic	
   adipose	
   tissue	
   and	
   angiotensin	
   II-­-induced	
   abdominal	
   aortic	
  
           aneurysm	
  formation.	
  Arterioscler	
  Thromb	
  Vasc	
  Biol.	
  2009;	
  29(10):1458-­-64.	
  

     118. Greenstein	
  AS,	
  Khavandi	
  K,	
  Withers	
  SB,	
  Sonoyama	
  K,	
  Clancy	
  O,	
  Jeziorska	
  M,	
  et	
  al.	
  
           Local	
   inflammation	
   and	
   hypoxia	
   abolish	
   the	
   protective	
   anticontractile	
   properties	
   of	
  
           perivascular	
  fat	
  in	
  obese	
  patients.	
  Circulation.	
  2009;	
  119(12):1661-­-70.	
  

     119. Eringa	
   EC,	
   Bakker	
   W,	
   van	
   Hinsbergh	
   VW.	
   Paracrine	
   regulation	
   of	
   vascular	
   tone,	
  
           inflammation	
   and	
   insulin	
   sensitivity	
   by	
   perivascular	
   adipose	
   tissue.	
   Vascul	
   Pharmacol.	
  
           2012	
  May-­-Jun;	
  56(5-­-6):204-­-9.	
  	
  

     120. Rittig	
  K,	
  Staib	
  K,	
  Machann	
  J,	
  Böttcher	
  M,	
  Peter	
  A,	
  Schick	
  F	
  et	
  al.	
  Perivascular	
  fatty	
  
           tissue	
   at	
   the	
   brachial	
   artery	
   is	
   linked	
   to	
   insulin	
   resistance	
   but	
   not	
   to	
   local	
   endothelial	
  
           dysfunction.	
  Diabetologia.	
  2008;	
  51(11):2093-­-9.	
  	
  

     121. Feldon	
   SE,	
   O'loughlin	
   CW,	
   Ray	
   DM,	
   Landskroner-­-Eiger	
   S,	
   Seweryniak	
   KE,	
   Phipps	
  
           RP.	
  Activated	
  human	
  T	
  lymphocytes	
  express	
  cyclooxygenase-­-2	
  and	
  produce	
  proadipogenic	
  
           prostaglandins	
   that	
   drive	
   human	
   orbital	
   fibroblast	
   differentiation	
   to	
   adipocytes.	
   Am	
   J	
  
           Pathol.	
  2006;	
  169(4):1183-­-93.	
  

     122. Chatterjee	
  TK,	
  Stoll	
  LL,	
  Denning	
  GM,	
  Harrelson	
  A,	
  Blomkalns	
  AL,	
  Idelman	
  G,	
  et	
  al.	
  
           Proinflammatory	
  phenotype	
  of	
  perivascular	
  adipocytes:	
  influence	
  of	
  high-­-fat	
  feeding.	
  Circ	
  
           Res	
  2009;	
  104(4):541.	
  

     123. Payne	
   GA,	
   Borbouse	
   L,	
   Kumar	
   S,	
   Neeb	
   Z,	
   Alloosh	
   M,	
   Sturek	
   M,	
   et	
   al.	
   Epicardial	
  
           perivascular	
   adipose-­-derived	
   leptin	
   exacerbates	
   coronary	
   endothelial	
   dysfunction	
   in	
  
           metabolic	
   syndrome	
   via	
   a	
   protein	
   kinase	
   C-­-beta	
   pathway.	
   Arterioscler	
   Thromb	
   Vasc	
   Biol.	
  
           2010;	
  30(9):1711-­-7.	
  	
  

     124. Takaoka	
   M,	
   Suzuki	
   H,	
   Shioda	
   S,	
   Sekikawa	
   K,	
   Saito	
   Y,	
   Nagai	
   R,	
   et	
   al.	
   Endovascular	
  
           injury	
   induces	
   rapid	
   phenotypic	
   changes	
   in	
   perivascular	
   adipose	
   tissue.	
   Arterioscler	
  
           Thromb	
  Vasc	
  Biol.	
  2010;	
  30(8):1576–82.	
  

     125. Henrichot	
   E,	
   Juge-­-Aubry	
   CE,	
   Pernin	
   A,	
   Pache	
   JC,	
   Velebit	
   V,	
   Dayer	
   JM,	
   et	
   al.	
  
           Production	
   of	
   chemokines	
   by	
   perivascular	
   adipose	
   tissue:	
   a	
   role	
   in	
   the	
   pathogenesis	
   of	
  
           atherosclerosis?	
  Arterioscler	
  Thromb	
  Vasc	
  Biol.	
  2005;	
  25(12):2594–9.	
  

                                                                                                                            	
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