Page 113 - 76_04
P. 113
VOL. 76 (4), 541-571, 2010 EL PREMIO NOBEL EN QUÍMICA 2010
figuration of natural dynemicin A. Chem. Biol. 2: 33-43. c) Avendaño, C. & Me-
néndez, J. C. (2008) “Medicinal Chemistry of Anticancer Drugs”, Ed. Elsevier,
capítulo 4, sección 8, pp. 122-126.
33. Negishi, E., Liu, S.-Y., Xu, C. & Huo, S. (2002) A Novel Highly Selective, and
General Methodology for the Synthesis of 1,5-Diene-Containing Oligoiso-
prenoids of All Possible Geometrical Combinations Exemplified by an Iterative
and Convergent Synthesis of Coenzyme Q10. Org. Lett. 4: 261-264.
34. Duncia, J. V., Chiu, A. T., Carini, D. J., Gregory, G. B., Johnson, A. L., Price, W.
A., Wells, G. J., Wong, P. C., Calabrese, J. C. & Timmermans, P. B. M. W. M.
(1990) The discovery of potent nonpeptide angiotensin II antagonists: a new
class of potent antihypertensives. J. Med. Chem. 32: 1312-329.
35. Waldmann, H., He, Y.-P., Tan, H., Arve, L. & Arndt, H.-D. (1994) Efficient
Synthesis of Losartan. A Nonpeptide Angiotensin II Receptor Antagonist. J. Org.
Chem. 59. 6391-6394.
36. a) Waldmann, H., He, Y. P., Arve, L. & Arndt, H. D. (2008) Flexible total synthe-
sis of biphenomycin B. Chem. Commun. 43: 5562-5564. b) Carbonnelle, A-C. &
Zhu, J. (2000) A Novel Synthesis of Biaryl-containing Macrocycles by a Domi-
no Miyaura Aryloboronate Formation: Intramolecular Suzuki Reaction. Org.
Lett. 2: 3477-3480.
37. a) Nicolaou, K. C., David, Y.-K., Chen, X.-H., Taotao, L., Marco, B. & Scott, A.
S. (2004) Chemistry and Biology of Diazonamide A: A first total synthesis and
confirmation of the true structure. J. Am. Chem. Soc. 126: 12888-12896. b) Ni-
colaou, K. C., Juliang, H., Mali, V. R., Paraselli, B. R., Gerasimos, R., Scott, A.
S., Xianhay, H., David, Y.-K., William, E. B., Gioseppone, N., Giannakakou, P.
& O’Brete, A. (2004) Chemistry and biology of Diazonamide A: Second Total
Synthesis and Biological Investigations. J. Am. Chem. Soc. 126: 12897-12906.
38. Vedejs, E. & Zajac, M. A. (2001) Synthesis of the Diazonamide A Macrocyclic
core via a Dieckmann-Type Cycization. Org. Lett. 3: 2451-2454.
39. Dufour, J., Neuville, L. & Zhu, J. (2010) Intramolecular Suzuki-Miyaura reac-
tion for the total synthesis of signal peptidase inhibitors arylomycins A(2) and
B(2). Chem. Eur. J. 16: 10523-10534.
40. Jia, Y., Bois-Choussy, M. & Zhu, J. (2008) Synthesis of diastereomers of comples-
tatin and chloropeptin I: Substrate-dependent atropstereoselectivity of the intra-
molecular Suzuki-Miyaura reaction. Angew. Chem. Int. Ed. Engl. 47: 4167-4172.
41. Nicolaou, K. C., Ramphal, J. I., Palazon, J. M. & Spanevello, R. A. (1989) Ste-
reocontrolled Total Synthesis of (5S,6R)-, (5S,6S)-, (5R,6R)-, and (5R,6S)-
(7E,9E,11Z,14Z)-5,6-Dihydroxy-7,9,11,14-icosatetraenoic Acid (5,6-DiHETE)
Methyl Esters. Angew. Chem. Int. Ed. 28. 587-588.
42. Suzuki, A. (1985) Organoboron compounds in new synthetic reactions.
Pure&Applied Chemistry. 57: 1749-1759.
* Información de contacto:
Dra. María del Carmen Avendaño López.
Catedrática de Química Orgánica y Académica de Número de la RANF.
e-mail: avendano@farm.ucm.es
571