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VOL. 72 (4), 599-609, 2006 VANADIUM IN VIVO INTERACTION WITH CEFATOXINE
If there were a lower concentration of free cefotaxime, it would
not reach the minimum inhibitory concentration to kill the
microorganism that cause the infection, so that the activity of
cefotaxime will decrease or even the cephalosporin will not have
activity in many cases. So, in poisoned patients with vanadium, it is
very important to bear in mind this fact when they have to follow a
course of treatment with cefotaxime.
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Quim. 19: 37-47.
(2) CRESSMAN, W. A.; SUGITA, E. T.; DOLUISIO, J. T.; NIEBERGAL, P. J. (1969): Cupric
ion-catalyzed hidrolysis of Penicellins: Mechanism and sites of complexation.
J. Pharm. Sci. 58: 1471-1476.
(3) DOADRIO, A. L.; DOADRIO, J. C.; IRIBARREN, M. (1992): Metal-ions catalyzed
hidrolysis of Ampicillin: RPHPLC-IEXHPLC Kinetic studies. Ecl. Quim. 17:
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(5) DOADRIO, A.; MIRASIERRA, M. G. (1973): Determinación espectrofotométrica de
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(6) MAYORGA, A. (1999): Interacción de metales tóxicos con Ceftriaxona: complejos
con Cu y V. Thesis presented to obtain the Doctor grade. University Complu-
tense. Madrid.
(7) CHI-HUA SUN; HUI-PO WANG (1998): Methods in the preparation of D-
Phenylglycine containg cefotaxime. J. Food and Drugs Anal. 6: 477-484.
(8) BLANCHAR, J. (1981): Evaluation of the relative efficacy of various techniques
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(9) PATEL, K. B.; NICOLAU, D. P.; NIGHTINGALE, C. H., QUINTIALINI, R. (1995):
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