Page 18 - 70_03
P. 18

LENNART K. PAALZOW  AN. R. ACAD. NAC. FARM.

FIGURE 13. A Bayesian estimate of the patient in Fig. 12 predicts that the patient
            should be given a dose of 0.5 mL perphenazin every second week.

                                      CONCLUSION

    In my presentation I have given you some examples on how
pharmacokinetics could be applied in clinical practice in order to
optimize drug therapy. Bayesian estimates based on previous
knowledge of the pharmacokinetics in a specific patient population
and a single plasma concentration value is a technique that gives the
possibility to estimate the desired drug dosing in an individual pa-
tient. There is still much research to do before we have reached the
goals of individualizing drug dosing and I personally think that phar-
macists and especially clinical pharmacists can do a lot in order to
reach this goal.

678
   13   14   15   16   17   18   19   20   21   22   23