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D. FERREIRA Y COLS. ANAL. REAL ACAD. NAL. FARM
The naproxen release profiles from the eight different microcap-
sules formulations are shown in Figure 3 and 4. The drug release profiles
were plotted against time and some mathematical models (Zero-order,
First-order and Higuchi Law) were applied.
Figure 3. Release profiles of A (RS PM), B (RL PO), C (RS PM/RL PO
75/25), D (RS PM/RL PO 50/50) and E (RS PM/RL PO 25/75) formulations.
Naproxen released (%) 100 A
B
80 C
D
60 E
40
20
0
0 2 4 6 8 10 12
Time (h)
144
