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ANALESRANFwww.analesranf.comNotably, the strength of our work is based on thestudy design, a systematic review that compiles theevidence on microbiota composition in children withOw or OB. Out of 409 articles,16 articles were selectedfor this systematic review. with regard to the results,it is worth mentioning that some of them are supportedby previous findings in adult populations with obesity. 4. CONCLUSIONThis systematic review compiled the evidence on thestructural characteristics of gut microbiota in childrenand adolescents with OB or metabolically unhealthyobesity compared to those with normal weight, throughobservational and intervention studies. It%u2019s known thatAt the class-level analysis, a higher abundance ofClostridia was found in two studies after intervention.In the 2%u00b0 study, which consisted of a combined strengthand endurance training program in children with OBcompared to normal weight subjects, a higherabundance of Clostridia was observed (30). Similarly,study 4%u00b0, which implemented a weight reductionprogram in children/adolescents with OB compared tonormal weight, also reported a higher proportion ofClostridia (32).Our article has limitations and strengths. Onelimitation is that we excluded subjects diagnosed withdiseases such as autism, diabetes, or suffering fromother relevant health conditions. Another limitation isthat there were 16 articles that fulfill the inclusioncriteria. Gut microbiota composition in pediatric populations with obesity: a systematic reviewMarti, A., Canas I y Tamez H. 131 An. R. Acad. Farm.Vol. 90. n%u00ba 1 (2024) %u00b7 pp. 125-135Table 3: Summary of intervention studies regarding changes in microbiota composition after lifestyle interventions inchildren/adolescents with OW/OB