Page 57 - 74_04

VOL. 74 (4) PROSTANOIDS ACTIONS IN CARDIOVASCULAR...

(62) FITZGERALD, G. A. AND PATRONO, C. (2001) The coxibs, selective inhibitors of
cyclooxygenase-2. N. Engl. J. Med. 345: 433-442.

(63) BELTON, O. AND FITZGERALD, D. (2003) Cyclooxygenase-2 inhibitors and
atherosclerosis. J. Am. Coll. Cardiol. 41: 1820-1822.

(64) FITZGERALD, G. A. (2003) COX-2 and beyond: Approaches to prostaglandin
inhibition in human disease. Nat. Rev. Drug. Discov. 2: 879-890.

(65) MURATA, T.; USHIKUBI, F.; MATSUOKA, T.; HIRATA, M.; YAMASAKI, A.;
SUGIMOTO, Y.; ICHIKAWA, A.; AZE, Y.; TANAKA, T.; YOSHIDA, N.; UENO, A.;
OH-ISHI, S. AND NARUMIYA, S. (1997) Altered pain perception and
inflammatory response in mice lacking prostacyclin receptor. Nature. 388:
678-682.

(66) CHENG, Y.; WANG, M.; YU, Y.; LAWSON, J.; FUNK, C. D. AND FITZGERALD, G.
A. (2006) Cyclooxygenases, microsomal prostaglandin E synthase-1, and
cardiovascular function. J. Clin. Invest. 116: 1391-1399.

(67) RUDIC, R. D.; BRINSTER, D.; CHENG, Y.; FRIES, S.; SONG, W. L.; AUSTIN, S.;
COFFMAN, T. M. AND FITZGERALD, G. A. (2005) COX-2-derived prostacyclin
modulates vascular remodeling. Circ. Res. 96: 1240-1247.

(68) FRANCOIS, H.; ATHIRAKUL, K.; HOWELL, D.; DASH, R.; MAO, L.; KIM, H. S.;
ROCKMAN, H. A.; FITZGERALD, G. A.; KOLLER, B. H. AND COFFMAN, T. M.
(2005) Prostacyclin protects against elevated blood pressure and cardiac
fibrosis. Cell. Metab. 2: 201-207.

(69) ROSS, R. (1999) Atherosclerosis--an inflammatory disease. N. Engl. J. Med.
340: 115-126.

(70) HANSSON, G. K. AND LIBBY, P. (2006) The immune response in atherosclerosis:
a double-edged sword. Nat. Rev. Immunol. 6: 508-519.

(71) VILA, L. (2004) Cyclooxygenase and 5-lipoxygenase pathways in the vessel
wall: role in atherosclerosis. Med. Res. Rev. 24: 399-424.

(72) KOBAYASHI, T.; TAHARA, Y.; MATSUMOTO, M.; IGUCHI, M.; SANO, H.;
MURAYAMA, T.; ARAI, H.; OIDA, H.; YURUGI-KOBAYASHI, T.; YAMASHITA, J.
K.; KATAGIRI, H.; MAJIMA, M.; YOKODE, M.; KITA, T. AND NARUMIYA, S.
(2004) Roles of thromboxane A(2) and prostacyclin in the development of
atherosclerosis in apoE-deficient mice. J. Clin. Invest. 114: 784-794.

(73) CIPOLLONE, F.; PRONTERA, C.; PINI, B.; MARINI, M.; FAZIA, M.; DE CESARE, D.;
IEZZI, A.; UCCHINO, S.; BOCCOLI, G.; SABA, V.; CHIARELLI, F.; CUCCURULLO,
F. AND MEZZETTI, A. (2001) Overexpression of functionally coupled
cyclooxygenase-2 and prostaglandin E synthase in symptomatic
atherosclerotic plaques as a basis of prostaglandin E(2)-dependent plaque
instability. Circulation. 104: 921-927.

(74) BANFI, C.; COLLI, S.; ELIGINI, S.; MUSSONI, L. AND TREMOLI, E. (2002)
Oxidized LDLs influence thrombotic response and cyclooxygenase 2.
Prostaglandins Leukot Essent Fatty Acids 67: 169-173.

(75) BURLEIGH, M. E.; BABAEV, V. R.; OATES, J. A.; HARRIS, R. C.; GAUTAM, S.;
RIENDEAU, D.; MARNETT, L. J.; MORROW, J. D.; FAZIO, S. AND LINTON, M. F.

21