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An. R. Acad. Nac. Farm., 2008, 74: 379-386
Artículo original
Common mechanism of recognition
and binding of the complementary molecules,
carbohydrate-lectin, in the verticillium disease
of Agaricus bisporus and Pleurotus ostreatus
cultivated mushrooms
Recibido el 15 de abril de 2008
AMELIA PÉREZ CABO and CONCEPCIÓN GARCÍA MENDOZA *
Centro de Investigaciones Biológicas-CSIC, Madrid
ABSTRACT
The carbohydrate-lectin interaction between the isolated glucogalactomannan
of Verticillium fungicola cell walls, and lectins, either from Agaricus bisporus or
Pleurotus ostreatus fruit bodies, was compared in order to establish the molecular
mechanism of the «dry bubble» or verticillium disease exhibited in the commercial
cultures of both edible mushrooms. This interaction between complementary
molecules, «target molecules», appears to be due to the terminal galactose linked
at (1-4) to the (1-6) mannose bone of the V. fungicola glucogalactomannan molecule.
Key words: «Dry bubble».—Verticillium disease.—Verticillium fungicola
glucogalactomannan.—Agaricus bisporus lectin.—Pleurotus ostreatus lectin.
* Académica Correspondiente de la Real Academia Nacional de Farmacia.
Centro de Investigaciones Biológicas-CSIC.
Ramiro de Maeztu, 9. 28040 Madrid (Spain).
Telf.: +34918373112. Fax: +34-915360432
E-mail: cgm@cib.csic.es
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