Page 58 - 70_03

M.a ELVIRA LÓPEZ-OLIVA Y COLS. AN. R. ACAD. NAC. FARM.

(27) lance by lowering body protein degradation in fed growing pigs. Am. J.
(28) Physiol. Endocrinol. Metab. 278: E477-E483.
(29) NØRRELUND, H.; NAIR, K.S.; JØRGESEN, J.O.L.; CHRISTIANSEN, J.S.; MØLLER, N.
(30) (2001) The protein-retaining effects of growth hormone during fasting in-
(31) volve inhibition of muscle-protein breakdown. Diabetes. 50: 96-104.
SÊVE, B.; BALLEVRE, O.; NOBLET, J.; PRUGNAUD, J.; OBLED, C. (1993) Recombi-
(32) nant porcine somatotropin and dietary protein enhance protein synthesis in
(33) growing pigs. J. Nutr. 123: 529-540.
(34) BATES, P.C. y PELL, J.M. (1991) Action and interaction of growth hormone
and the ß-agonist clenbuterol on growth, body composition and protein
(35) turnover in dwarf mice. Br. J. Nutr. 65: 115-129.
(36) CARTER-SU, C.; SCHWARTZ, J.; SMITH, L.S. (1996) Molecular mechanism of
growth hormone action. Annu. Rev. Physiol. 58: 187-207.
(37) DAUGHADAY, W.H. (1997) From sulphation factor to IGF-I, 40 years of resear-
(38) ch on the regulation of cartilage growth. In: TAKANO, K.; HIZUKA, N.; TAKAHAS-
(39) HI, S. (ed). The 4th International Symposium on Insulin-like growth factors.
(40) Elsevier. Tokyo. Japan.
DAUGHADAY, W.H.; HALL, K.; RABEN, M.S.; SALMON, JR. W.D.; BRANDE, J.L.
WYK, J.J. (1972) Somatomedin: proposed designation for sulphation factor.
Nature 235: 107-109.
ISAKSSON, O.G.; LINDAHL, A.; NILSSON, A.; ISGAARD, J. (1987) Mechanism of the
stimulatory effect of growth hormone on longitudinal bone growth. Endocr.
Rev. 8: 426-438.
LI, H.; BARTOLD, P.M.; ZHANG, C.Z.; CLARKSON, R.W.; YOUNG, W.G.; WATERS,
M.J. (1998) Growth hormone and insulin growth factor I induce bone mor-
phogenetic proteins 2 and 4: a mediator role in bone and tooth formation?
Endocrinology, 139: 3855-3862.
BILLESTRUP, N. y NIELSEN, J.H. (1991) The stimulatory effect of growth hor-
mone, prolactin, and placental lactogen on ß-cell proliferation is not media-
ted by insulin-like growth factor -I. Endocrinology 129: 883-88.
SJÖGREN, K.; LIU, J.L.; BLAD, K.; SKRTIC, S.; VIDAL, O.; WALLENIUS, V.; LEROITH,
D.; TORNELL, J.; ISAKSSON, O.G.P.; JANSSON, J.O.; OHLSSON, C. (1999) Liver-
derived insulin-like growth factor-I is the principal source of IGF-I in blood
but is not required for postnatal body growth in mice. Proc. Natl. Acad. Sci.
USA. 96: 7088-7092.
YAKAR, S.; LIU, J.L.; STANNARD, B.; BUTLER, A.; ACCILI, D.; SAUER, B.; LEROITH,
D. (1999) Normal growth and development in absence of hepatic insulin-
like growth factor-I. Proc. Natl. Acad. Sci. USA. 96: 7324-7329.
LIU, J.L. y LEROITH, D. (1999) Insulin-like growth factor I is essential for
postnatal growth in response to growth hormone. Endocrinology, 140: 5178-
5184.
LEROITH, D.; BONDY, C.; YAKAR, S.; LIU, J.L.; BUTLER, A. (2001) The somato-
medin hypothesis: 2001. Endocr. Rev. 22: 53-74.
FLINT, D.J. y GARDNER, M.J. (1993) Influence of growth hormone deficiency
on growth and body composition in rats: site-specific effects upon adipose
tissue development. J. Endocrinol. 137: 202-211.

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