Page 47 - 81_03
P. 47

Functional characterization of P2Y1 and P2X4 receptors in human neuroblastoma SK-N-MC cells

     M, et al. Ca2+/calmodulin-dependent kinase II                 Minneman KP. Coexisting beta 1- and atypical beta-
     signalling cascade mediates P2X7 receptor-dependent           adrenergic receptors cause redundant increases in
     inhibition of neuritogenesis in neuroblastoma cells.          cyclic AMP in human neuroblastoma cells. Mol
     FEBS J 2009; 276: 5307-25.                                    Pharmacol 1992; 42: 753-9.

7. Ortega F, Pérez-Sen R, Morente V, Delicado EG, Miras-      20. Schaak S, Cayla C, Blaise R, Quinchon F, Paris H.
     Portugal MT. P2X7, NMDA and BDNF receptors                    HepG2 and SK-N-MC: two human models to study
     converge on GSK3 phosphorylation and cooperate to             alpha-2 adrenergic receptors of the alpha-2C subtype.
     promote survival in cerebellar granule neurons. Cell          J Pharmacol Exp Ther 1997; 281: 983-91.
     Mol Life Sci 2010; 67: 1723-33.
                                                              21. Sidhu A., Fishman PH. Identification and
8. Morente V, Pérez-Sen R, Ortega F, Huerta-Cepas J,               characterization of functional D1 dopamine receptors
     Delicado EG, Miras-Portugal MT. Neuroprotection               in a human neuroblastoma cell line. Biochem Biophys
     elicited by P2Y13 receptors against genotoxic stress by       Res Commun 1990; 166: 574-9.
     inducing DUSP2 expression and MAPK signaling
     recovery. Biochim Biophys Acta 2014; 1843: 1886-         22. Gordon EA, Kohout TA, Fishman PH.
     98.                                                           Characterization of functional neuropeptide Y
                                                                   receptors in a human neuroblastoma cell line. J
9. Ortega F, Pérez-Sen R, Miras-Portugal MT. Gi-coupled            Neurochem 1990; 55: 506-13.
     P2Y-ADP receptor mediates GSK-3 phosphorylation
     and ß-catenin nuclear translocation in granule           23. Fisher SK, Landon RE. Identification of multiple
     neurons. J Neurochem 2008; 104: 62-73.                        phosphoinositide-linked receptors on human SK-N-
                                                                   MC neuroepithelioma cells. J Neurochem 1991; 57:
10. Lustig KD, Shiau AK, Brake AJ, Julius D. Expression            1599-608.
     cloning of an ATP receptor from mouse
     neuroblastoma cells. Proc Natl Acad Sci USA 1993;        24. Sidhu A, Olde B, Humblot N, Kimura K, Gardner N.
     90: 5113-17.                                                  Regulation of human D1 dopamine receptor function
                                                                   and gene expression in SK-N-MC neuroblastoma
11. Kaiho H, Matsuoka I, Kimura J, Nakanishi H.                    cells. Neuroscience 1999; 91: 537-47.
     Identification of P2X7 (P2Z) receptor in N18TG-2
     cells and NG108-15 cells. J Neurochem 1998; 70:          25. Chan AS, Ng LW, Poon LS, Chan WW, Wong YH.
     951-57.                                                       Dopaminergic and adrenergic toxicities on SK-N-MC
                                                                   human neuroblastoma cells are mediated through G
12. Sak K, Samuel K, Kelve M, Webb TE.                             protein signaling and oxidative stress. Apoptosis
     Pharmacological characterisation of pyrimidinoceptor          2007; 12: 167-79.
     responses in NG108-15 cells. Eur J Pharmacol 2001;
     415: 127-33.                                             26. Chen J, Rusnak M, Luedtke RR, Sidhu A. D1
                                                                   dopamine receptor mediates dopamine-induced
13. Larsson KP, Hansen AJ, Dissing S. The human SH-                cytotoxicity via the ERK signal cascade. J Biol Chem
     SY5Y neuroblastoma cell-line expresses a functional           2004; 279: 39317-30.
     P2X7 purinoceptor that modulates voltage-dependent
     Ca2+ channel function. J Neurochem 2002; 83: 285-98.     27. Sheriff S, Qureshy AF, Chance WT, Kasckow JW,
                                                                   Balasubramaniam A. Predominant role by CaM kinase
14. Raffaghello L, Chiozzi P, Falzoni S, Di Virgilio F,            in NPY Y1 receptor signaling: involvement of CREB.
     Pistoia V. The P2X7 receptor sustains the growth of           Peptides 2002; 23: 87-96.
     human neuroblastoma cells through a substance P-
     dependent mechanism. Cancer Res 2006; 66: 907-14.        28. Bahouth SW, Sowinski KM, Lima JJ. Regulation of
                                                                   human ß1-adrenergic receptors and their mRNA in
15. Wu PY, Lin YC, Chang CL, et al. Functional decreases           neuroepithelioma SK-N-MC cells: effects of agonist,
     in P2X7 receptors are associated with retinoic acid-          forskolin, and protein kinase A. Biochem Pharmacol
     induced neuronal differentiation of Neuro-2a                  2001; 62: 1211-20.
     neuroblastoma cells. Cell Signal 2009; 21: 881-91.
                                                              29. Chan AS, Yeung WW, Wong YH. Integration of G
16. Cavaliere F, Nestola V, Amadio S, et al. The                   protein signals by extracellular signal-regulated
     metabotropic P2Y4 receptor participates in the                protein kinases in SK-N-MC neuroepithelioma cells. J
     commitment to differentiation and cell death of human         Neurochem 2005; 94: 1457-70.
     neuroblastoma SH-SY5Y cells. Neurobiol Dis 2005;
     18: 100-9.                                               30. Recuero M, Serrano E, Bullido MJ, Valdivieso F. Aß
                                                                   production as consequence of cellular death of a
17. Sak K, Webb TE, Samuel K, Kelve M, Jarv J. Only                human neuroblastoma overexpressing APP. FEBS
     pyrimidinoceptors are functionally expressed in               Lett 2004, 570: 114-8.
     mouse neuroblastoma cell lines. Mol Cell Biol Res
     Commun 1999; 1: 203-8.                                   31. Sebastia J, Pertusa M, Vilchez D, et al. Carboxyl-
                                                                   terminal fragment of amyloid precursor protein and
18. Lee H, Choi BH, Suh BC, Lee SK, Kim KT.                        hydrogen peroxide induce neuronal cell death through
     Attenuation of signal flow from P2Y6 receptor by              different pathways. J Neural Transm 2006; 113: 1837-
     protein kinase C-a in SK-N-BE(2)C human                       45.
     neuroblastoma cells. J Neurochem 2003; 85: 1043-53.
                                                              32. Sopher BL, Fukuchi K, Smith AC, Leppig KA,
19. Esbenshade TA, Han C, Theroux TL, Granneman JG,                Furlong CE, Martin GM. Cytotoxicity mediated by

@Real Academia Nacional de Farmacia. Spain                                                   255
   42   43   44   45   46   47   48   49   50   51   52