Page 214 - 80_01
P. 214
Krishna
Naik&
col.
VIg:
H,
CH3,
CH3C6H4,
260
oC,
72
%,
C27H30N6O3,
C:66.64(66.48),
H:6.17(6.05),
N:17.20(17.07),
O:9.87(9.70).
VIh:
H,
CH3,
ClC6H4,
265
oC,
76
%,
C26H27N6O3Cl,
VIh:
C:61.59(61.45),
H:5.33(5.19),
N:16.58(16.45),
O:9.47(9.32),
Cl:7.00(6.85).
VIi:
H,
CH3,
OCH3C6H4,
270
oC,
70
%,
C27H30N6O4.,C:64.54(64.42),
H:5.97(5.81),
N:16.73(16.59),
O:12.74(12.60).
VIj:
H,
CH3,
NO2C6H4,
272
oC,
72
%,
C26H27N7O5,
C:60.34(60.20),
H:5.22(5.07),
N:18.95(18.82),
O:15.47(15.30).
e.
IR
(KBr)
Spectral
data
(?max
in
cm--1)
VIa:
3185
(NH),
1665
(C=O),
1600
(C=N)
VIb:
3175
(NH),
1670
(C=O),
1602
(C=N)
VIc:
3200
(NH),
1665
(C=O),
1605
(C=N)
VId:
3190
(NH),
1670
(C=O),
1604
(C=N)
VIe:
3210
(NH),
1650
(C=O),
1605
(C=N)
VIf:
3215
(NH),
1660
(C=O),
1602
(C=N)
VIg:
3195
(NH),
1670
(C=O),
1605
(C=N)
VIh:
3190
(NH),
1675
(C=O),
1604
(C=N)
VIi:
3205
(NH),
1660
(C=O),
1605
(C=N)
VIj:
3180
(NH),
1660
(C=O),
1604
(C=N)
f.
1H
NMR
(DMSO--d6)
Spectral
data
(d
in
ppm)
VIa:
1.52
(s,
3H,
CH3),
2.35
(s,
3H,
N=C--CH3),
6.8
(s,
H,
Ar--NH),
7.0
(s,
2H,
O--CH2--CO),
7.1
–
7.3
(m,
10H,
Ar–H),
7.4
(d,
2H,
C6H4),
7.58
(d,
2H,
Ar--H),
7.7
(d,
2H,
C6H4),
10.92
(s,
H,
NH)
VIg:
1.50
(s,3H,
CH3),
2.26
(s,
3H,
CH3),
2.33
(s,
3H,
N=C--CH3),
6.8
(s,
H,
Ar--NH),
7.1--7.3(m,
9H,
Ar--H),
7.23
(s,
2H,
O--CH2--CO),
7.4
(d,
2H,C6H4),
7.7
(d,
2H,
Ar,C6H4),
10.90
(s,
H,
NH),
VIh:
1.58
(s,
3H,
CH3),
2.39
(s,
3H,
N=C--CH3),
6.8
(s,
H,
Ar--NH),
7.1--7.3
(m,
9H,
Ar--H),
7.27
(s,
2H,
O--CH2--CO),
7.4
(d,
2H,
C6H4),
7.7
(d,
2H,
C6H4),
10.94
(s,
H,
NH)
VIi:
1.53
(s,
3H,
CH3),
2.37
(s,
3H,
N=C--CH3),
6.8
(s,
H,
Ar--NH),
7.1--7.3
(m,
9H,
Ar--H),
7.26
(s,
2H,
O--CH2--CO),
7.4
(d,
2H,
C6H4),
7.7
(d,
2H,
C6H4),
10.93
(s,
H,
NH)
VIj:
1.48
(s,
3H,
CH3),
2.30
(s,
3H,
N=C--CH3),
6.8
(s,
H,
Ar--NH),
7.1--7.3
(m,
9H,
Ar--H),
7.20
(s,
2H,
O--CH2--CO),
7.4
(d,
2H,
C6H4),
7.7
(d,
2H,
C6H4),
10.89
(s,
H,
NH)
g.
Elemental
analysis
data
of
compounds
VII
(--R,
--R1=CH3,
--R2,
M.P.,
Yield,
Molecular
formula,
Element:
Found
%,
(Calc
%
))
VIIa:
H,
4|--C6H5,
240
oC,
75
%,
C28H30N6O4,
C:65.36(65.23),
H:5.83(5.70),
N:16.34(16.21),
O:12.45(12.30).
VIIb:
CH3,
4|--C6H5,
245
oC,
77
%,
C29H32N6O4,
C:65.90(65.72),
H:6.06(5.92),
N:15.90(15.75),
O:12.12(12.00).
VIIc:
OCH3,
4|--C6H5,
235
oC,
72
%,
C29H32N6O4,
C:63.91(63.76),
H:5.88(5.74),
N:15.44(15.30),
O:14.70(14.56).\
VIId:
OC2H5,
4|--C6H5,
250
oC,
73
%,
C30H34N6O5,
C:64.51(64.37),
H:6.09(5.94),
N:15.05(14.92),
O:14.33(14.18).
VIIe:
Cl,
4|--C6H5,
230
oC,
75
%,
C28H29N6O4Cl,
C:61.25(61.10),
H:5.28(5.12),
N:15.31(15.19),
O:11.66(11.44),
Cl:6.47(6.33).
VIIf:
Br,
4|--C6H5,
255
oC,
78
%,
C28H29N6O4Br,
C:56.67(56.50),
H:4.89(4.66),
N:14.16(14.02),
O:10.79(10.52),
Br:13.47(13.30).
VIIg:
H,
4|--CH3C6H4,
260
oC,
72
%,
C29H32N6O4,
C:65.90(65.72),
H:6.06(5.87),
N:15.90(15.78),
O:12.12(11.95).
VIIh:
H,
4|--ClC6H4,
265
oC,
76
%,
C28H29N6O4Cl,
C:61.36(61.21),
H:5.11(5.00),
N:15.34(15.20),
O:11.68(11.47),
Cl:6.17(6.02).
VIIi:
H,
4|--OCH3C6H4,
270
oC,
70
%,
C27H30N6O4,
C:64.34(64.17),
H:5.97(5.78),
N:16.73(16.58),
O:12.74(12.60).
VIIj:
H,
4|--NOC6H4,
272
oC,
72
%,
C26H27N6O5,
C:60.34(60.15),
H:5.22(5.08),
N:18.95(18.80),
O:15.74(15.62).
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