Page 85 - 78_04
P. 85

MIND	
  LINES	
  AGAINST	
  GUIDELINES	
  IN	
  TREATMENT	
  OF	
  MALARIA	
  …	
  	
  

	
  
and	
   dispensaries),	
   secondary	
   level	
   health	
   care	
   facilities	
   (tehsil	
   headquarter	
  
hospitals	
   and	
   district	
   head	
   quarter	
   hospitals)	
   and	
   tertiary	
   level	
   health	
   care	
  
facilities	
   (tertiary	
   hospitals,	
   post	
   graduate	
   medical	
   institutes,	
   teaching	
   hospitals).	
  
All	
   the	
   tertiary	
   healthcare	
   facilities	
   have	
   a	
   primary	
   section	
   for	
   treating	
   common	
  
disease	
  including	
  malaria.	
  	
  

        Cases	
   are	
   referred	
   from	
   lower	
   to	
   higher	
   level	
   depending	
   on	
   severity	
   of	
  
problem	
   and	
   available	
   infrastructure	
   (8).	
   The	
   study	
   population	
   included	
   all	
   the	
  
public	
   and	
   private	
   tertiary	
   health	
   care	
   facilities	
   treating	
   malaria	
   in	
   Islamabad	
   and	
  
Rawalpindi.	
   A	
   list	
   of	
   all	
   the	
   public	
   and	
   private	
   tertiary	
   healthcare	
   facilities	
   was	
  
obtained	
   from	
   respective	
   District	
   Health	
   Offices.	
   All	
   the	
   20	
   public	
   and	
   private	
  
tertiary	
   healthcare	
   facilities	
   were	
   selected	
   for	
   the	
   study	
   and	
   the	
   sample	
   size	
   was	
  
Islamabad	
   (n	
   =10,	
   5	
   each	
   public	
   and	
   private	
   healthcare	
   facilities)	
   and	
   Rawalpindi	
  
(n	
  =10,	
  5	
  each	
  public	
  and	
  private	
  healthcare	
  facilities).	
  	
  

        For	
   assessing	
   the	
   prescribing	
   practices	
   in	
   each	
   facility,	
   thirty	
   patients	
  
treated	
  for	
  malaria	
  by	
  the	
  prescribers	
  over	
  the	
  last	
  one	
  year	
  were	
  reviewed	
  (7).	
  	
  

        A	
   total	
   of	
   600	
   patient	
   encounters	
   i.e.	
   300	
   from	
   each	
   sector	
   (public	
   and	
  
private)	
   healthcare	
   facilities	
   situated	
   in	
   both	
   cities	
   were	
   collected	
   randomly	
   from	
  
daily	
   registers,	
   medical	
   records,	
   prescriptions,	
   patient-­-held	
   records.	
   At	
   least	
   two	
  
patients	
   encounter	
   per	
   month	
   during	
   the	
   low	
   season	
   (October	
   till	
   April)	
   and	
   four	
  
patients	
   encounter	
   per	
   month	
   during	
   the	
   high	
   season	
   (May	
   till	
   September)	
   for	
  
malaria	
  were	
  selected.	
  	
  

        As	
  there	
  is	
  no	
  trend	
  of	
  laboratory	
  confirmation	
  of	
  malaria	
  in	
  Pakistan	
  all	
  the	
  
prescriptions	
   with	
   diagnosis	
   of	
   malaria,	
   anti-­-malarial	
   drugs	
   and	
   tests	
   of	
   malaria	
  
parasite	
   results	
   were	
   included	
   in	
   the	
   sample.	
   Plasmodium	
   vivax	
   is	
   common	
   in	
  
Rawalpindi	
   and	
   Islamabad	
   so	
   the	
   adherence	
   of	
   prescribers	
   with	
   standard	
  
treatment	
  regimen	
  for	
  P.vivax	
  was	
  assessed.	
  	
  

        Interview	
   of	
   the	
   head	
   of	
   the	
   outpatient	
   department	
   on	
   recommended	
  
current	
  prescribing	
  practices	
  in	
  the	
  healthcare	
  facilities	
  were	
  recorded	
  and	
  applied	
  
to	
  all	
  encounters	
  where	
  records	
  were	
  missing	
  (9).	
  Prescriptions	
  without	
  the	
  name	
  
of	
   the	
   prescriber	
   and	
   folder	
   without	
   patient’s	
   information	
   were	
   excluded.	
   The	
  
prescribers	
  were	
  identified	
  from	
  patient’s	
  prescriptions	
  and	
  information	
  regarding	
  
their	
  designation	
  and	
  experience	
  was	
  recorded.	
  

Data	
  collection	
  and	
  analysis	
  

	
  	
   Data	
   was	
   collected	
   by	
   the	
   principal	
   investigator	
   along	
   with	
   two	
   teams	
  
comprised	
   of	
   five	
   trained	
   data	
   collectors	
   in	
   each	
   team	
   trained	
   by	
   the	
   group	
   of	
  
experts	
  including	
  principal	
  investigator	
  (9).	
  	
  

        The	
   data	
   collectors	
   were	
   trained	
   students	
   of	
   the	
   final	
   year	
   Doctor	
   of	
  
Pharmacy	
   program	
   who	
   tallied	
   data	
   with	
   standard	
   treatment	
   regimen.	
   Data	
   were	
  

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