Page 84 - 78_04
P. 84

M.	
  MALIK	
  &	
  col	
  

	
  
2.	
  MATERIALS	
  AND	
  METHODS	
  

Study	
  design	
  

        A	
   comparative,	
   cross-­-sectional	
   study	
   was	
   designed	
   to	
   evaluate	
   the	
   case	
  
records	
   of	
   patients	
   from	
   October	
   2010-­-	
   2011	
   including	
   (daily	
   registers,	
   medical	
  
records,	
   prescriptions,	
   patient-­-held	
   records)	
   treated	
   for	
   malaria	
   in	
   public	
   and	
  
private	
   tertiary	
   healthcare	
   facilities	
   in	
   the	
   twin	
   cities,	
   namely	
   Islamabad	
   (federal	
  
capital)	
  and	
  Rawalpindi.	
  	
  

Study	
  tool	
  

        The	
  case	
  records	
  were	
  collected	
  from	
  the	
  male	
  and	
  female	
  medicine	
  wards	
  
and	
  out-­-patient	
  departments	
  (OPD)	
  of	
  the	
  healthcare	
  facilities.	
  A	
  pre-­-validated	
  tool	
  
i.e.	
   WHO	
   prescribing	
   indicator	
   form	
   was	
   used	
   to	
   collect	
   data	
   regarding	
   current	
  
prescribing	
  practices	
  for	
  the	
  treatment	
  of	
  malaria(7).	
  	
  

        The	
  prescribing	
  form	
  included	
  five	
  core	
  indicators	
  such	
  as	
  %	
  of	
  encounters	
  
having	
   diagnosis,	
   average	
   number	
   of	
   drugs	
   per	
   encounter,	
   %	
   average	
   number	
   of	
  
antibiotics	
   and	
   injections	
   prescribed	
   per	
   encounter	
   and	
   %	
   of	
   drugs	
   prescribed	
   by	
  
generic	
  names.	
  Beside	
  this	
  few	
  additional	
  indices	
  such	
  as	
  demographics	
  of	
  patient,	
  
type	
   of	
   drug	
   combinations	
   prescribed	
   and	
   availability	
   of	
   standard	
   treatment	
  
guidelines	
  in	
  the	
  healthcare	
  facilities	
  were	
  also	
  assessed.	
  	
  

        Prescriptions	
   were	
   also	
   assessed	
   for	
   the	
   prescribed	
   anti-­-malarial	
   drugs,	
  
their	
   doses,	
   strengths,	
   frequencies	
   and	
   durations	
   of	
   use	
   to	
   check	
   whether	
   if	
   they	
  
followed	
   national	
   standard	
   treatment	
   regimen	
   or	
   not.	
   The	
   minimum	
   requirement	
  
for	
   the	
   adherence	
   of	
   prescriptions	
   with	
   standard	
   treatment	
   regimen	
   was	
  
elaborated	
  and	
  transformed	
  into	
  measurable	
  adherence	
  indicators	
  scale.	
  The	
  scale	
  
included	
   five	
   indicators	
   including	
   correct	
   prescribing	
   of	
   right	
   anti-­-malarial	
   drug,	
  
its	
  dose,	
  strength,	
  frequency	
  and	
  duration	
  of	
  use.	
  The	
  composite	
  score	
  for	
  the	
  scale	
  
was	
   5-­-10	
   and	
   lower	
   score	
   referred	
   to	
   better	
   adherence	
   with	
   the	
   standard	
  
treatment	
  regimen.	
  

        Data	
   collection	
   was	
   planned	
   and	
   permission	
   for	
   survey	
   was	
   obtained	
   from	
  
relevant	
   district	
   health	
   officers	
   (DHO)	
   and	
   Medical	
   superintendents	
   (MS)	
   of	
  
respective	
   healthcare	
   facilities.	
   The	
   study	
   was	
   also	
   approved	
   by	
   Malaria	
   Control	
  
Program,	
  Ministry	
  of	
  Health,	
  Government	
  of	
  Pakistan.	
  	
  

Sampling	
  of	
  facilities	
  and	
  patient	
  encounters	
  

        Keeping	
   in	
   view	
   the	
   federal	
   administrative	
   and	
   regulatory	
   structure	
   of	
   the	
  
country	
   and	
   due	
   to	
   location	
   and	
   operation	
   of	
   Malaria	
   Control	
   Program	
   in	
   the	
  
capital	
   city,	
   two	
   main	
   cities	
   of	
   Pakistan	
   namely	
   Islamabad	
   and	
   Rawalpindi	
   were	
  
selected	
   for	
   the	
   study.	
   The	
   public	
   healthcare	
   facilities	
   providing	
   services	
   at	
  
provincial	
  and	
  district	
  levels	
  are	
  categorized	
  as:	
  primary	
  level	
  health	
  care	
  facilities	
  
(basic	
   health	
   units,	
   rural	
   health	
   centers,	
   mother	
   &	
   child	
   health	
   centers,	
   TB	
   clinics	
  

502	
  

	
  
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