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POTENTIAL$USE$OF$LECTINS$

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We!did!not!find!any!general!correlations!between!sialic!acids,!CEA,!CA!1969!

and! a6fetoprotein! concentration! values! and! the! affinity! of! the! ligands! for! the!
lectins!in!the!sera!assayed!(data!not!shown).!

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Figure!1.6!Effect!of!lecitin!concentration!on!LEL!fixation.!

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Figure!2.6!Effect!of!lecitin!concentration!on!LEL!fixation.!

4.)DISCUSSION)

The! approximate! recurrence! rates! following! curative! resection! of!
adenocarcinoma! of! the! colon! and! rectum! are! estimated! as! follows:! 30%! for!
sigmoid! and! rectum,! 20%! for! right! colon! and! 10%! for! transverse! and! left! colon!
(17).!

! The!follow6up!the!health!status!of!operated!colorectal!cancer!subjects!with!
additional! criteria! to! those! now! established! seems! to! be! an! important! aim.!
Furthermore,! these! assays! would! be! much! easier! to! perform! on! sera! than! in!
pathological!tissue!samples!obtained!after!surgical!operations.!

! In! a! previous! paper! (15),! we! discussed! in! this! view! the! usefulness! of! the!
determination!of!the!activities!of!several!glycosidases!and!cathepsin!L!in!the!era!of!
colorectal! operated! subjects! 4! months! after! surgery.! Now,! we! propose! the! use! of!
certain!lectins!for!the!follow6up!of!the!operated,!769!months!after!surgical!exeresis.!

125$

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