Page 98 - 76_01
P. 98
DAVID LEÓN NAVARRO Y COLS. AN. R. ACAD. NAC. FARM.
24. Fountain, S. J. & North, R. A. (2006) A C-terminal lysine that controls human
P2X4 receptor desensitization. J. Biol. Chem. 281: 15044-15049.
25. Tulapurkar, M. E.; Zundorf, G. & Reiser, G. (2006) Internalization and desen-
sitization of a green fluorescent protein-tagged P2Y nucleotide receptor are
differently controlled by inhibition of calmodulin-dependent protein kinase II.
J. Neurochem. 96: 624-634.
26. Xue, Y.; Zhou, F.; Zhu, M.; Ahmed, K.; Chen, G. & Yao, X. (2005) GPS: a
comprehensive www server for phosphorylation sites prediction. Nucleic Acids
Res. 33: W184-187.
27. Gasteiger, E.; Gattiker, A.; Hoogland, C.; Ivanyi, I.; Appel, R. D. & Bairoch, A.
(2003) ExPASy: The proteomics server for in-depth protein knowledge and
analysis. Nucleic Acids Res. 31: 3784-3788.
28. Obenauer, J. C.; Cantley, L. C. & Yaffe, M. B. (2003) Scansite 2.0: Proteome-
wide prediction of cell signaling interactions using short sequence motifs.
Nucleic Acids Res. 31: 3635-3641.
29. Tokumitsu, H.; Chijiwa, T.; Hagiwara, M.; Mizutani, A.; Terasawa, M. & Hi-
daka, H. (1990) KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-
4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent pro-
tein kinase II. J. Biol. Chem. 265: 4315-4320.
30. Sumi, M.; Kiuchi, K.; Ishikawa, T.; Ishii, A.; Hagiwara, M.; Nagatsu, T. &
Hidaka, H. (1991) The newly synthesized selective Ca2+/calmodulin depen-
dent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h
cells. Biochem. Biophys. Res. Commun. 181: 968-975.
31. Pankratov, Y.; Lalo, U.; Verkhratsky, A. & North, R. A. (2006) Vesicular relea-
se of ATP at central synapses. Pflugers Arch. 452: 589-597.
32. Kim, M.; Jiang, L. H.; Wilson, H. L.; North, R. A. & Surprenant, A. (2001)
Proteomic and functional evidence for a P2X7 receptor signalling complex.
EMBO J. 20: 6347-6358.
33. Colbran, R. J. (2004) Targeting of calcium/calmodulin-dependent protein ki-
nase II. Biochem. J. 378: 1-16.
34. Gargett, C. E. & Wiley, J. S. (1997) The isoquinoline derivative KN-62 a potent
antagonist of the P2Z-receptor of human lymphocytes. Brit. J. Pharmacol. 120:
1483-1490.
35. Humphreys, B. D.; Virginio, C.; Surprenant, A.; Rice, J. & Dubyak, G. R.
(1998) Isoquinolines as antagonists of the P2X7 nucleotide receptor: high
selectivity for the human versus rat receptor homologues. Mol. Pharmacol.
54: 22-32.
* Información de contacto:
Dra. María Teresa Miras-Portugal.
Department of Biochemistry and Molecular Biology IV. Faculty of Veterinary.
Complutense University of Madrid, Spain.
Avda. Complutense, s/n. 28040, Madrid. Spain.
Telf.: +34 91 394 38 94. Fax: +34 91 394 39 09
Email: mtmiras@vet.ucm.es
22
