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VOL. 75 (2), 217-231, 2009 (CU)II IN VIVO INTERACTION WITH CEFOTAXIME

Table 5. Activity of cefotaxime against B. subtilis CECT 356 and E. coli CECT
434 and CECT 516

Concentration of Diameter of the
cefotaxime in Moles halo in mm

B. subtilis CECT 356 16.5.10–6 47
E. coli CECT 434 3.3.10–6 32
E. coli CECT 516 1.65.10–6 33
0.82.10–6 31
0.33.10–6 25
0.655.10–6 21
1.125.10–6 16
0.062.10–6 16
0.031.10–6 15
0.012.10–6 12
0.655.10–6 22
0.062.10–6 18
0.031.10–6 16
0.012.10–6 14

Table 6. Activity of cefotaxime against S. aureus spp aureus CECT 239 and
CECT 435

Diameter of the halo in mm

TSA Media Agar-blood Media

Concentration S. aureus S. aureus spp S. aureus S. aureus
of cefotaxime spp aureus spp aureus spp aureus spp aureus
CECT 239 CECT 435 CECT 239 CECT 435

16.5.10–6 33 37 27 30
3.3.10–6 27 29 21 24
1.65.10–6 27 27 18 23
0.82.10–6 24 25 15 20

0.33.10–6 19 23 12 17

As expected, cefotaxime was active against E. coli studied (Table
5), but some differences would be observed: strikingly E. coli CECT

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