Page 83 - 75_02
P. 83
VOL. 75 (2), 217-231, 2009 (CU)II IN VIVO INTERACTION WITH CEFOTAXIME
animals because of the decrease of the free cefotaxime concentration
due to the metal.
Table 3. Differences more significant in concentrations of free cefotaxime
between rats with copper and without it
SAMPLES TIME (MIN) P VALUE OF T
BLOOD 150 0.04 2.34
LIVER
30 0.02 2.7
90 0.02 2.9
120 1.47.10–4 6.73
150 0.02 2.8
180 1.57.10–3 4.68
210 6.36.10–8 18.9
90 7.27.10–3 3.57
150 0.02 2.9
SPLEEN 180 1.14.10–4 6.98
210 2.50.10–4 6.23
60 4.34.10–4 5.74
90 1.12.10–7 15.57
KIDNEY 120 5.10–4 5.61
150 5.46.10–3 3.77
180 4.88.10–4 5.64
30 4.93.10–5 7.86
60 1.39.10–4 6.8
LUNG 90 1.35.10–3 4.8
120 5.46.10–3 3.77
180 0.04 2.45
210 1.28.10–3 4.84
30 6.39.10–4 5.4
HEART 120 6.16.10–3 3.68
180 8.72.10–3 3.44
210 1.19.10–6 12.9
227
