Page 94 - 73_03
P. 94
VOL. 73 (3), 703-746, 2007 ARE ADRENOMEDULLIN POSITIVE MODULATORS NOVEL...
(25) - An Integrated Software System for Modeling Organic and Bioorganic
(26) Molecules Using Molecular Mechanics. J. Comput. Chem. 11: 440-467.
PETITJEAN, M. (1998): Interactive maximal common 3D substructure searching
(27) with the combined SDM/RMS algorithm. Computers & Chemistry 22: 463-
(28) 465.
(29) MORRIS, G. M.; GOODSELL, D. S.; HALLIDAY, R. S.; HUEY, R.; HART, W. E.; BELEW,
R. K. and OLOSN, A. J. (1998): Automated docking using a Lamarckian genetic
(30) algorith and an empirical binding free energy function. J. Comput. Chem. 19:
1639-1662.
(31) STOTE, R. H. and KARPLUS, M. (1995): Zinc binding in proteins and solution:
(32) a simple but accurate nonbonded representation. Proteins 23: 12-31.
ALBERTS, I. L.; NADASSY, K. and WODAK, S. J. (1998): Analysis of zinc binding
(33) sites in protein crystal structures. Protein Sci. 7: 1700-1716.
(34) MACPHERSON, L. J.; BAYBURT, E. K.; CAPPARELLI, M. P.; CARROLL, B. J.; GOLDSTEIN,
R.; JUSTICE, M. R.; ZHU, L.; HU, S.; MELTON, R. A.; FRYER, L.; GOLDBERG, R. L.;
(35) DOUGHTY, J. R.; SPIRITO, S.; BLANCUZZI, V.; WILSON, D.; O’BYRNE, E. M.; GANU, V.
(36) and PARKER, D. T. (1997): Discovery of CGS 27023A, a non-peptidic, potent,
(37) and orally active stromelysin inhibitor that blocks cartilage degradation in
rabbits. J. Med. Chem. 40: 2525-2532.
DANIELS, J. T.; SCHULTZ, G. S.; BLALOCK, T. D.; GARRETT, Q.; GROTENDORST, G. R.;
DEAN, N. M. and KHAW, P. T. (2003): Mediation of transforming growth factor-
beta(1)-stimulated matrix contraction by fibroblasts: a role for connective
tissue growth factor in contractile scarring. Am. J. Pathol. 163: 2043-52.
BERMAN, H. M.; WESTBROOK, J.; FENG, Z.; GILLILAND, G.; BHAT, T. N.; WEISSIG, H.;
SHINDYALOV, I. N. and BOURNE, P. E. (2000): The Protein Data Bank. Nucleic
Acids Res. 28: 235-242.
FENG, Y. Q.; LIKOS, J. J.; ZHU, L. M.; WOODWARD, H.; MUNIE, G.; MCDONALD,
J. J.; STEVENS, A. M.; HOWARD, C. P.; DE CRESCENZO, G. A.; WELSCH, D.; SHIEH,
H. S. and STALLINGS, W. C. (2002): Solution structure and backbone dynamics
of the catalytic domain of matrix metalloproteinase-2 complexed with a
hydroxamic acid inhibitor. Biochim. Biophys. Acta 1598: 10-23.
LUKACOVA, V.; ZHANG, Y.; MACKOV, M.; BARICIC, P.; RAHA, S.; CALVO, J. A.
and BALAZ, S. (2004): Similarity of binding sites of human matrix
metalloproteinases. J. Biol. Chem. 279: 14194-14200.
TAKAHASHI, K.; IKURA, M.; HABASHITA, H.; NISHIZAKI, M.; SUGIURA, T.; YAMAMOTO,
S.; NAKATANI, S.; OGAWA, K.; OHNO, H.; NAKAI, H. and TODA, M. (2005): Novel
matrix metalloproteinase inhibitors: Generation of lead compounds by the in
silico fragment-based approach. Bioorg. Med. Chem. 13: 4527-4543.
MORGUNOVA, E.; TUUTTILA, A.; BERGMANN, U.; ISUPOV, M.; LINDQVIST, Y.;
SCHNEIDER, G. and TRYGGVASON, K. (1999) Structure of human pro-matrix
metalloproteinase-2: Activation mechanism revealed. Science 284: 1667-1670.
BERGMANN, U.; TUUTTILA, A.; MORGUNOVA, E. and TRYGGVASON, K. Crystal
Structure of Human Mmp-2. (to be published).
DHANARAJ, V.; WILLIAMS, M. G.; YE, Q.; MOLINA, F.; JOHNSON, L. L.; ORTWINE, D.
F.; PAVLOVSKY, A.; RUBIN, J. R.; SKEEAN, R. W.; WHITE, A. D.; HUMBLET, C.; HUPE,
D. J. and BLUNDELL, T. L. (1999): X-ray Structure of Gelatinase A Catalytic
723