Page 64 - 73_03
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BERNARD PORTHA AN. R. ACAD. NAC. FARM.
(31) BIHOREAU, M. T.; KTORZA, A.; KINEBANYAN, M. F. and PICON, L. (1986): Impaired
(32) glucose homeostasis in adult rats from hyperglycemic mothers. Diabetes. 35:
(33) 979-984.
(34) PATEL, M. S. and SRINIVASAN, M. (2002): Metabolic programming: causes and
consequences. J. Biol. Chem. 277: 1629-1632.
(35) GAUGUIER, D.; BIHOREAU, M. T.; KTORZA, A.; BERTHAULT, M. F. and PICON, L.
(36) (1990): Inheritance of diabetes mellitus as consequence of gestational
hyperglycemia in rats. Diabetes. 39: 734-739.
(37) ABDEL-HALIM, S. M.; GUENIFI, A.; HE, B.; YG, B.; MUSTAFA, M.; HOJEBERG, B.;
HILLERT, J.; BAKHIET, M. and EFENDIC, S. (1998): Mutations in the promoter of
(38) adenylylcyclase (AC)-III gene, overexpression of AC-III mRNA and enhanced
(39) cAMP generation in islets from the spontaneously diabetic GK rat model of
Type2 diabetes. Diabetes. 47: 498-504.
(40) GALLI, J.; LI, S.; BARNARD, C.; OSTENSON, C. G.; JIAO, H.; FAKHRAID-RAD, H.; JACOB,
H. J.; LandER, E. S. and LUTHMAN, H. (1996): Genetic analysis of non-insulin-
dependent diabetes mellitus in the GK rat. Nature Genet. 12: 31-37.
WALLIS, R. H.; WALLACE, K. J.; COLLINS, S. C.; MCATEER, M.; ARGOUD, K.;
BIHOREAU, M. T.; KAISAKI, P. J. and GAUGUIER, D. (2004): Enhanced insulin
secretion and cholesterol metabolism in congenic strains of the spontaneously
diabetic (type2) Goto Kakizaki rat are controlled by independent genetic loci
in rat chromosome 8. Diabetologia. 47: 1096-1106.
LIN, J. M.; ORTSÄTER, H.; FAKHRAID-RAD, H.; GALLI, J.; LUTHMAN, H. and BERGSTEN,
P. (2001): Phenotyping of individual pancreatic islets locates genetic defects
in stimulus secretion coupling to Niddm1i within the major diabetes locus in
GK rats. Diabetes. 50: 2737-2743.
DRUCKER, D. J. (2006): The biology of incretin hormones. Cell. Metabolism.
3: 1531-165.
TOURREL, C.; BAILBÉ, D.; LACORNE, M.; MEILE, M. J.; KERGOAT, M. and PORTHA,
B. (2002): Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat
model by expansion of the beta-cell mass during the prediabetic period with
Glucagon-like peptide-1 or Exendin-4. Diabetes. 51: 1452-1452.
DOLZ, M.; BAILBÉ, D.; MOVASSAT, J.; LE STUNFF, H.; KASSIS, N.; GIROIX, M. H. and
PORTHA, B. (2006): Pivotal role of cAMP in the acute restitution of defective
glucose-stimulated insulin release in diabetic GK rat by GLP-1. Diabetes. 55:
Suppl 1, A371.
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