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E. MUÑOZ Y M.ª E. LÓPEZ-OLIVA AN. R. ACAD. NAC. FARM.

(39) DONOVAN, W.H., GIUDICE, L.C., MURPHY, L.J., HINTZ, R.L., ROSENFELD. R. (1991)
(40) Maternal insulin-like growth factor-binding protein messenger ribonucleic
acid during rat pregnancy. Endocrinology 129: 3359-3366.
(41) GARGOSKY, S.E., MOYSE, K.J., WALTON, P.E., OWENS, J.A., WALLACE, J.C., RO-
(42) BINSON, J.S., OWENS, P.C. ( 1990) Circulating levels of insulin-like growth
(43) factors increase and molecular forms of their serum binding proteins chan-
ge with human pregnancy. Biochem. Biophys. Res. Commun. 170: 1157-
(44) 1163.
(45) HILLS, F.A., ENGLISH, J., CHARD, T. (1996) Circulating levels of IGF-I and
(46) IGF-binding protein-I throughout pregnancy. Relation to birthweight and
(47) maternal weight. J. Endocrinol. 148: 303-309.
(48) NASON, K.S., BINDER, N.D., LABARTA, J.I., ROSENFELD, R.C., GARGOSKY, S.E.
(49) (1996) IGF-II and IGF-binding proteins increase dramatically during rab-
(50) bit pregnancy. J. Endocrinol. 148: 121-130.
(51) HAN, V.K.M., BASSET, N.S., WALTON, J., CHALLIS, J.R.G. (1996) The expres-
sion of insulin-like growth factor (IGF) and IGF-binding protein (IGFBP)
genes in the human placenta and membranes: evidence for IGF-IGFBP
interactions at the feto-maternal interface J. Clin. Endocrinol. Metab. 81(7):
2680-2693.
LIU, L., HARDING, J.E., EVANS, P.C., GLUCKMAN, P.D. (1994) Maternal insulin-
like growth factor-I infusion alters feto-placental carbohydrate and protein
metabolism in pregnant sheep. Endocrinology 135: 895-900.
HARDING, J.E., LIU, L., EVANS, P.C., GLUCKMAN, P.D (1994) Insulin-like growth
factor 1 alters feto-placental protein and carbohydrate metabolism in fetal
sheep. Endocrinology 134:1509-1515.
WANG, H.S., LIM, J., ENGLISH, J., IRVINE L., CHARD T. (1991) The concentra-
tion of insulin-like growth factor I (IGF-l) and insulin-like growth factor
binding protein (IGFBP-I) in human umbilical cord serum at delivery:
relation to fetal weight. J. Endocrinol. 129: 459-464.
GARGOSKY, S.E., NANTO-SALONEN, K., TAPANAIMEN, P., ROSENFELD, R.G. (1993)
Pregnancy in growth hormone-deficient rats assessment of insulin-like
growth factors (IGFs), IGF-binding proteins (IGFBPs) and IGFBP protease
activity. J. Endocrinol. 136: 479-489.
SOHLSTRÖM, A., KATSMAN, A., KIND, K.L., ROBERTS, C.T., OWENS, P.C., ROBIN-
SON, J.S., OWENS, J.A. (1998) Food restriction alters pregnancy-associated
changes in IGF-I and IGFBP in the guinea pig. Am. J. Physiol. 274 (Endo-
crinol. Metab). 37: E410-E416.
PEKONEN, F., SUIKKARI, A.M., MAKINEN, T., RUTANEN E.M. (1988) Different
insulin-like growth factor binding species in human placenta and deciduas.
J. Clin. Endocrinol. Metab. 67: 1250-1257.
GARGOSKY, S.E., OWENS, J.A., WALTON, P.E., BALLARD, F.J. (1991) Administra-
tion of insulin-like growth factor I, but not growth hormone, increases
maternal weight in late pregnancy without affecting fetal or placental
growth. J.Endocrinol. 130: 395-400.
KHUN-SHERLOCK,B., BACK,P., BLAIR, H.T., MC CUTCHEON, S.N.; BREIER, B.H.;
GLUCKMAN, P.D. (1996) The effect of bGH and rhIGF-I treatment en mater-

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