Page 43 - 69_01

M. CASCALES ANAL. REAL ACAD. NAL. FARM.

BIBLIOGRAFÍA

(1) ACEHAN. D. ET AL. (2002). Three dimensional structure of the apoptosome:
implications for assembly, procaspase-9 binding, and activation. Mol. Cell 9: 423-
432.

(2) ADAMS, J.M. AND CORY, S. (2001). Life or death decisions by the Bcl-2 protein
family. Trends in Biochem. Sci. 26: 61-66.

(3) ADRIAN, C. AND MARTIN S.J. (2001). The mitochondrial apoptosome: a killer
unleashed by the cytochrome seas. Trends in Biochem. Sci. 26: 390-397.

(4) BAUD, V. AND KARIN, M. (2001). Signal transduction by tumor necrosis factor
and its relatives. Trends in Cell Biology 11: 372-377.

(5) BEERE, H. et al (2000). Heat shock protein 70 inhibits apoptosis by preventing
recruitment of procaspase-9 to the Apaf-1 apoptosome. Nature Cell Biol. 2: 469-
475.

(6) CHAI, J. et al. (2001). Crystal structure of a procaspase-7 zymogen. Mechanisms
of activation and substrate binding. Cell 107: 399-407.

(7) CHAI, J. et al. (2001). Structural basis of Caspase-7 inhibition by XIAP. Cell 104:
769-780.

(8) COLEMAN, M.L. et al. (2001). Membrane blebbing during apoptosis results from
caspase-mediated activation of ROCK1. Nature Cell Biology 3: 339-345.

(9) DENG, Y., LIN, Y. AND WU, X. (2002). TRAIL induced apoptosis requires Bax-
dependent mitochondrial release of Smac/DIABLO. Genes Dev. 16: 33-45.

(10) DU, C. et al., (2000). Smac, a mitochondrial protein that promotes cytochrome c-
dependent caspase activation by eliminating IAP inhibition. Cell 102: 33-42.

(11) EARNSHAW, W.C., MARTINS, L.M. AND KAUFMANN, S.H. (1999). Mammalian
caspases: structure, activation, substrates and functions during apoptosis. Ann.
Rev. Biochem. 68: 383-424.

(12) ELLIS HM Y HORVITZ HR (1986) Genetic control of programmed cell death in the
nematode C.elegans. Cell 44, 817-829

(13) FINUCANE, D.M. et al (1999). Bax induced caspase activation and apoptosis via
cytochrome c release from mitochondria is inhibitable by Bcl-XL. J. Biol. Chem.
274: 2225-2233.

(14) JOZA, N., SUSIN, S. A., et al., (2001). Essential role of the mitochondrial Apop-
tosis Inducing Factor in programmed cell death. Nature, 410, 549-554.

(15) JUIN, P. et al. (1999). c-myc induced sensitization to apoptosis is mediated
through cytochrome c. Genes Dev. 13: 1367-1381.

(16) KERR JF, WYLLIE AH Y CURRIE AR (1972) Br J Cancer 26, 239-257.

60