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VOL. 75 (3), 389-418, 2009 CENTRAL AND PERIPHERAL ENDOGENOUS MORPHINE

possible to characterise the presence of endogenous morphine
unambiguously in various mammalian tissues, both central and
peripheral.

Figure 2. Intermediates on the morphine synthetic pathway in mammals:
enzymes that may be involved. This synthetic pathway can take place in particu-
lar cells, but might also involve uptake of intermediates (e.g. dopamine) by other
cells that will finish the morphine synthesis.

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