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VOL. 73 (2), 537-566, 2007 ECTO-NUCLEOTIDASES, MOLECULAR PROPERTIES...
FIGURE 1. Hallmarks of nucleotide research with particular emphasis on
signaling via extracellular nucleotides. ATP was first discovered in 1929 and
in the 1980ies and 1990ies the molecular and functional identity of prototype
members of all ecto-nucleotidase families and of nucleoside and nucleotide
receptor families was uncovered (for references see text). Ado, adenosine;
A2 receptor, adenosine A2 receptor; AP, alkaline phosphatase (human placental).
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