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VOL. 71 (4), 821-833, 2005 CHOLINERGIC CURRENTS IN XENOPUS...
When the membranes were obtained from oocytes injected with
hippocampus membranes, we found the same results as described in
cerebral cortex, except that no differences between the agonist were
detected.
FIGURE 1. Effects of nicotinic agonists on the size of the currents at a holding po-
tential of –90 mV with an exposure of 40 s. In this case the membranes were from
frontal cortex. (A) Muscarinic current induced by 3mM acetylcholine. (B) Muscarinic
current inhibited by 0.5 mM atropine. (Current obtained in the same oocyte as point
A). (C) Nicotinic current induced by 3 mM acetylcholine. (D) Nicotinic current indu-
ced by 3 mM nicotine. (E) Nicotinic current induced by 3 mM DMPP. (F) Nicotinic
current induced by 3 mM DMPP, note that in this case the channel closed before the
end of exposure to the agonist.
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