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ADENOSINE RECEPTORS

receptor Adenosine A2B receptor Adenosine A3 receptor
A2b, Rs; AA2BR AA3A

E-NECA, CV- None Cl-IB-MECA
ATL146e MRS1754j, enprofylline
MRS 1220, MRE 3008-F20,
H 58261f,g MRS 1191; MRS 1523
selective:

17387, CSC

0; [3H]-SCH ([3H]-ZM-241385; [3H]- [3H]- MRE 3008-F20
-241385 DPCPX)

[3H]-MRS1754

cial and non- Some commercial and non- Some commercial and non-
peptide commercial peptide antibodies commercial peptide antibodies

P29274, rat Human 328 aa, P29275, rat Human 318 aa, P33765, rat 320
, mouse 409 332 aa, P29276 mouse 332 aa, aa P28647(Alternative splicing in
UO5673 rat can yield product with 337 aa)
Mouse 320 aa, AF069778

Gs, Gq Gi

Intermediate levels: Intermediate levels: Cerebellum
(human?), hippocampus
GABAergic Blood vessels, eye, median (human?)
date-putamen, eminence, mast cells
(human?) Low levels: Most of brain (rat,
accumbens, Low levels: Adrenal gland, mouse).
olfactorium), pituitary gland

of brain

chr 17p11.2-12; chr 1p21-13,

sensorimotor Relaxation of smooth muscle Enhancement of mediator release
basal ganglia; from mast cells (some species).
f platelet in vasculature and intestine; Preconditioning (some species).

and inhibition of monocyte and 145

macrophage function,