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Tratamientos experimentales contra el virus Ébola Zaire

        Although neither a vaccine nor an effective antiviral treatment is currently
available for use in humans, the fundamental knowledge and experimental findings
already achieved, generate cautious optimism about the translation of these
findings into clinical practice for prevention and treatment of Ebola hemorrhagic
fever. However, it seems quite obvious that an effective progress will require
public financial support.

11. AGRADECIMIENTOS

        La autora desea expresar su agradecimiento al Dr. J. C. Menéndez por la
elaboración de algunas de las figuras.

12. REFERENCIAS

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     2. Feldmann, H.; Geisbert, T. W. Ebola haemorrhagic fever. Lancet, 377, 849-862 (2011).
     3. Ver, por ejemplo: (a) Bray, M.; Davis, K.; Geisbert, T.; Schmaljohn, C.; Huggins; J. A mouse

          model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever. J. Infect. Dis.
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          entry requires a compact hydrophobic fist at the tip of the fusion loop. J. Virol. 88, 6636-
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          Kuehne, A. I.; Kranzusch, P. J.; Griffin, A. M.; Ruthel, G.; Dal Cin, P.; Dye, J. M.; Whelan, S. P.;
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     9. Kanapathipillai, R.; Restrepo, A. N. H.; Fast, P.; Wood, D.; Dye, Ch.; Kieny, M.-P.; Moorthy, V.
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     10. Olinger, G. G.; Pettitt, J.; Kim, D.; Working, C.; Bohorov, O.; Bratcher, B.; Hiatt, E.; Hume, S. D.;
          Jhonson, A. K.; Morton, J.; Pauly, M.; Whaley, K. J.; Lear, C. M.; Biggins, J. E.; Scully, C.;
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          monoclonal antibodies provides protection in rhesus machaques. Proc. Natl. Acad. Sci. U S
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     11. Qiu, X.; Wong, G.; Audet, J.; Bello, A.; Fernando, L.; Alimonti, J. B.; Fausther-Bovendo, H.; Wei,
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          nonhuman primates with ZMapp. Nature 514, 47-53 (2014).
     12. La empresa retiró este producto del mercado en octubre de 2011.

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