Page 151 - 69_04

VOL. 69 (4) ADENOSINE RECEPTORS

(57) ISHIWATA, K., NOGUCHI, J., WAKABAYASHI, S., SHIMADA, J., OGI, N., NARIAI, T.,
TANAKA, A., ENDO, K., SUZUKI, F. AND SENDA, M. (2000) 11C-labeled KF18446:
a potential central nervous system adenosine A2a receptor ligand. J Nucl Med 41:
345-54

(58) JARVIS, M.F., JACKSON, R.H. AND WILLIAMS, M. (1989) Autoradiographic
characterization of high affinity adenosine A2 receptors in the rat brain. Brain Res
484: 111-8

(59) JARVIS, M.F., SCHULZ, R., HUTCHISON, A.J., DO, U.H., SILLS, M.A. AND
WILLIAMS, M. (1989) [3H]CGS 21680, a selective A2 adenosine receptor agonist
directly labels A2 receptors in rat brain. J Pharmacol Exp Ther 251: 888-93

(60) JARVIS, M.F. AND WILLIAMS, M. (1988) Differences in adenosine A-1 and A-2
receptor density revealed by autoradiography in methylxanthine-sensitive and
insensitive mice. Pharmacol Biochem Behav 30: 707-14

(61) JOHANSSON, B., AHLBERG, S., VAN DER PLOEG, I., BRENÉ, S., LINDEFORS, N.,
PERSSON, H. AND FREDHOLM, B.B. (1993) Effect of long term caffeine treatment
on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain.
Naunyn Schmiedebergs Arch Pharmacol 347: 407-14

(62) JOHANSSON, B., GEROGIEV, V. AND FREDHOLM, B.B. (1997) Distribution and
postnatal ontogeny of adenosine A2A receptors in rat brain: comparison with
dopamine receptors. Neuroscience 80: 1187-207

(63) JOHANSSON, B., HALLDNER, L., DUNWIDDIE, T.V., MASINO, S.A., POELCHEN, W.,
GIMÉNEZ-LLORT, L., ESCORIHUELA, R.M., FERNÁNDEZ-TERUEL, A., WIESENFELD-
HALLIN, Z., XU, X.-J., HARDEMARK, A., BETSHOLTZ, C., HERLENIUS, E. AND
FREDHOLM, B.B. (2001) Hyperalgesia, anxiety, and decreased hypoxic
neuroprotection in mice lacking the adenosine A1 receptor. Proc Natl Acad Sci U
S A 98: 9407-12

(64) KULL, B., SVENNINGSSON, P. AND FREDHOLM, B.B. (2000) Adenosine A2A
receptors are colocalized with and activate Golf in rat striatum. Mol Pharmacol 58:
771-7

(65) LATINI, S. AND PEDATA, F. (2001) Adenosine in the central nervous system:
release mechanisms and extracellular concentrations. J Neurochem 79: 463-84

(66) LEDENT, C., VAUGEOIS, J.M., SCHIFFMANN, S.N., PEDRAZZINI, T., EL YACOUBI,
M., VANDERHAEGHEN, J.J., COSTENTIN, J., HEATH, J.K., VASSART, G. AND
PARMENTIER, M. (1997) Aggressiveness, hypoalgesia and high blood pressure in
mice lacking the adenosine A2A receptor. Nature 388: 674-8

(67) LEE, K.S. AND REDDINGTON, M. (1986) Autoradiographic evidence for multiple
CNS binding sites for adenosine derivatives. Neuroscience 19: 535-49

(68) LEE, Y.C., CHANG, C.W., SU, C.W., LIN, T.N., SUN, S.H., LAI, H.L. AND CHERN,
Y. (1999) The 5' untranslated regions of the rat A2A adenosine receptor gene
function as negative translational regulators. J Neurochem 73: 1790-8

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